3 187 marketing skills from 354 authors. They cover promotion, ads, search and everything aimed at an audience. Half of them fit into 2 029 tokens or less — that is what one costs your context window when the agent loads it. 597 ship runnable scripts rather than instructions alone. 35 of them cannot work without an MCP server, most often rube. We also found 247 copies of these same skills sitting in other people's repositories — counted once here, not 247 times.
3 187 unique 354 authors 1 619 updated this month 129 from vendors
Understand why customers really buy by uncovering the \"job\" they're hiring your product to do Use when: **Understanding customer motivation** beyond demographics and feature requests; **Finding product-market fit** by identifying the real progress customers seek; **Discovering why customers switch** (or don't) between solutions; **Identifying true competition** that isn't obvious from industry categories; **Creating marketing messages** that resonate with real customer struggles
Imagine your project has failed spectacularly—then work backward to identify why. Apply Gary Klein's \"prospective hindsight\" technique to catch failures before they happen. Use when: **Before launching** a product, campaign, or major initiative; **Before making** an important decision (hiring, investment, partnership); **Starting a project** to identify risks the team hasn't considered; **When overconfident** and everyone agrees the plan is great; **Before committing resources** to a signific...
Master product positioning using April Dunford's proven 5+1 framework from \"Obviously Awesome\". Transform how customers perceive your product by deliberately setting the right context. Use when: Launching a new product and need to define market position; Current positioning feels \"off\" - customers don't \"get it\"; Facing price resistance or wrong competitor comparisons; Pivoting product to new market or segment; Preparing sales pitch and need positioning foundation
Design products around price using Madhavan Ramanujam's \"Monetizing Innovation\" methodology—determine willingness to pay before you build, not after. Use when: **Set pricing for a new product** before or during development; **Validate willingness to pay** before investing in features; **Structure pricing tiers** (Good-Better-Best) for different segments; **Choose the right monetization model** (subscription, usage-based, freemium, etc.); **Diagnose why a product isn't monetizing** as expected
Anticipate and neutralize every reason customers say \"no\" before they say it. Combine Chris Voss's negotiation psychology with systematic sales methodology to turn objections into opportunities. Use when: **Before sales calls** to prepare responses to common pushback; **After losing deals** to document and learn from objections; **Product positioning** to address concerns in marketing copy; **Pricing conversations** to defend value against price resistance; **Team training** to create an obje...
Create research-backed buyer personas that drive real marketing and product decisions. Combine Buyer Personas methodology with Jobs-to-be-Done to build profiles based on actual behavior, not demographics fiction. Use when: **Starting customer discovery** to define who you're validating with; **Marketing campaign planning** to target the right messages to right people; **Content strategy** to create content that resonates with specific audiences; **Product roadmap prioritization** to build fea...
Test willingness to pay before launching with proven pricing research methodologies. Combine Van Westendorp, Gabor-Granger, and behavioral techniques to find your optimal price point. Use when: **After solution validation** to test willingness to pay; **Before launch** to set initial pricing; **Pricing changes** to test new price points; **New segments** to understand price sensitivity by segment; **Competitive positioning** to price against alternatives
Conduct comprehensive keyword research to identify high-value search terms, map search intent, and uncover content gaps for SEO and content marketing.
Generate comprehensive marketing analytics reports by collecting KPIs, analyzing trends, and delivering actionable insights with attribution modeling and funnel analysis.
Create, adapt, and schedule social media content across platforms with platform-specific formatting, engagement hooks, and strategic posting cadence.
Optimize a webpage for search engines by analyzing on-page elements, improving technical performance, and implementing structured data for maximum visibility.
Enrich CRM records with firmographic and contact data, filling gaps in company and person profiles to improve segmentation, routing, and outreach quality.
Create tailored sales proposals and RFP responses that address prospect needs, articulate solution value, and include pricing, timelines, and social proof.
Write compelling, persuasive marketing and sales copy using proven frameworks like AIDA, PAS, BAB, and 4Ps, with tone and voice customization, CTA optimization, and A/B variant generation.
Analyze and categorize Bluesky accounts by topic using keyword extraction. Use when users mention Bluesky account analysis, following/follower lists, topic discovery, account curation, or network analysis.
Extract keywords from documents using YAKE algorithm with support for 34 languages (Arabic to Chinese). Use when users request keyword extraction, key terms, topic identification, content summarization, or document analysis. Includes domain-specific stopwords for AI/ML and life sciences. Optional deeper extraction mode (n=2+n=3 combined) for comprehensive coverage.
Generates WAFFLES Declarations for social media posts — preemptive lists of what a post does NOT say. Use when users mention WAFFLES, ask for clarifications on their post, want to prevent misinterpretation, or request disclaimers for controversial/nuanced takes.
Framework for competitive landscape analysis across any industry. Use when creating competitor analysis, market positioning assessments, investment memos, strategic reviews, or any analysis requiring systematic evaluation of competitive dynamics. Triggers include requests for competitive landscape decks, peer comparisons, market structure analysis, strategic positioning assessments, and investment recommendations.
Real DCF (Discounted Cash Flow) model creation for equity valuation. Retrieves financial data from SEC filings and analyst reports, builds comprehensive cash flow projections with proper WACC calculations, performs sensitivity analysis, and outputs professional Excel models with executive summaries. Use when users need to value a company using DCF methodology, request intrinsic value analysis, or ask for detailed financial modeling with growth projections and terminal value calculations.
Plan comprehensive marketing campaigns from strategy through execution. Develop campaign briefs, select optimal channels, create timelines, allocate budgets, define targeting parameters, design A/B testing strategies, and establish performance measurement frameworks.
Create and optimize email marketing campaigns including sequences, newsletters, drip campaigns. Design subject line strategies, develop segmentation approaches, implement A/B testing, and establish analytics tracking for email performance.
Optimize website content for search engine visibility and user engagement. Conduct keyword research, implement on-page SEO tactics, analyze content gaps, write compelling meta descriptions, and develop internal linking strategies.
Develop comprehensive social media strategies across multiple platforms. Create content calendars, establish posting schedules, design engagement tactics, plan influencer outreach, and structure paid social campaigns with ROI measurement.
File organization toolkit. Provides duplicate detection, file merging/splitting, pattern matching, text processing (like case conversion, word counting), and file classification by size or time.
> Goal-oriented binder design campaign planning and health assessment. (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.
> Guidance for choosing the right protein binder design tool. (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
> (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.
> Binder design campaign planning, monitoring, and troubleshooting. (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.
> Binder design tool selection and workflow routing guidance. (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
> Proteina-Complexa flow-based protein backbone generation with fold-conditioned sampling guidance. (2) Exploring long-chain backbone generation beyond standard diffusion baselines, (3) Using NVIDIA Proteina-style flow matching workflows for controllable backbone design, (4) Comparing flow-based backbone generation against RFdiffusion or BoltzGen, (5) Prototyping fold-guided backbone campaigns before sequence design. This skill is based on the public NVIDIA Digital Bio Proteina project and uses "Proteina-Complexa" as the BioClaw-facing skill label. For sequence design after backbone generation, use proteinmpnn or solublempnn. For QC thresholds, use protein-design-qc.
Workflow for foundational sequence parsing, conversion, compression handling, and interval-aware file validation.
Create, manipulate, and convert bedGraph files for genome browser visualization. Covers bedGraph format, conversion to/from bigWig, normalization, and signal processing. Use when handling coverage and signal tracks from ChIP-seq, ATAC-seq, or RNA-seq.
BED file format fundamentals, creation, validation, and basic operations. Covers BED3 through BED12 formats, coordinate systems, sorting, and format conversion using bedtools and pybedtools. Use when working with genomic coordinates or preparing interval files for downstream tools.
Perform flux balance analysis (FBA) and flux variability analysis (FVA) on genome-scale metabolic models using COBRApy. Predict growth rates, metabolic fluxes, and optimal resource utilization. Use when predicting metabolic phenotypes or optimizing flux distributions.
Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.
Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical conversion), DART-seq (Meyer 2019, APOBEC1-YTH fusion), m6Anet (nanopore direct RNA), or MeRIP-seq with calibration. Use when distinguishing antibody-based from antibody-free m6A detection methods, applying the DRACH motif constraint, reconciling cross-method disagreements (DART 44% in DRACH vs GLORI), or detecting m6Am at the cap.
Calls DNA methylation from Oxford Nanopore sequencing data using signal-level analysis. Use when detecting 5mC or 6mA modifications directly from nanopore reads without bisulfite conversion.
PLINK file formats, format conversion, and quality control filtering for population genetics. Convert between VCF, BED/BIM/FAM, and PED/MAP formats, apply MAF, genotyping rate, and HWE filters using PLINK 1.9 and 2.0. Use when working with PLINK format files or running QC.
Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.
> Structure prediction for protein, nucleic-acid, and small-molecule complexes with the Chai-1 foundation model (Chai Discovery 2024, github.com/chaidiscovery/chai-lab). Reach for this skill to predict an antibody-antigen or protein-ligand complex from a single FASTA, to re-fold designed binders as an AlphaFold-multimer alternative, or to drive co-folding from Python for batched campaigns on a GPU.
Evidence-grounded target validation scoring with GO/NO-GO decisions for drug discovery campaigns
NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
Use this skill whenever the user wants to automatically organize raw neuroimaging data (DICOM, NIfTI, EEG, etc.) into a valid BIDS (Brain Imaging Data Structure) dataset. Triggers include: 'organize to BIDS', 'BIDS organizer', 'convert to BIDS', 'BIDS conversion', 'bidsify', 'create BIDS dataset', 'raw data to BIDS', or any request to structure data according to BIDS specification.
Use this skill whenever the user wants to convert DICOM files or folders to NIfTI format (.nii or .nii.gz), extract neuroimaging volumes from clinical DICOM series (MRI, CT, PET, etc.), prepare raw DICOM data for research processing pipelines, anonymize while converting, or batch-convert multiple series/studies. Triggers include: 'DICOM to NIfTI', 'dcm to nii', 'convert dicom to nii.gz', 'dcm2niix', 'extract nii from dicom', 'batch dicom to nifti', 'prepare dicom for freesurfer/fsl/spm', 'anonymized nifti conversion', or any request to transform clinical DICOM data into analysis-ready NIfTI format while preserving orientation, voxel spacing, slice timing (when available), and important metadata in the JSON sidecar.
Use this skill whenever the user wants to convert NIfTI files (.nii or .nii.gz) to DICOM format, create DICOM series from processed neuroimaging results, write segmentation/registration/analysis outputs back to DICOM for PACS compatibility or clinical viewer comparison, or transfer metadata from reference DICOM files. Triggers include: mentions of 'NIfTI to DICOM', 'nii to dcm', 'convert nii.gz to DICOM', 'dicomify segmentation', 'nii2dcm', 'bring results back to DICOM', 'create DICOM from NIfTI', 'nii to dicom series', or any request to take post-processed neuroimaging results (segmentation, registration, bias field correction, synthesis, etc.) and store/view them alongside original patient DICOM data. Also use when modality-specific metadata (especially MR, SVR) or preservation of patient/study information from a reference DICOM is needed. Do NOT use for the reverse conversion (DICOM to NIfTI), non-medical imaging file conversions, or any clinical diagnostic or treatment-related workflows.
Search bioRxiv preprints through the official bioRxiv API and locally filter titles, abstracts, and authors for keyword queries. Use when you need recent biology preprints, bioRxiv-native metadata, date-range scans, DOI lookups, or author shortlists that may not yet appear in peer-reviewed literature indexes.
Orchestrate multi-simulation campaigns including parameter sweeps, batch jobs, and result aggregation. Use for running parameter studies, managing simulation batches, tracking job status, combining results from multiple runs, or automating simulation workflows.
Comprehensive metabolomics research skill for identifying metabolites, analyzing studies, and searching metabolomics databases. Integrates HMDB (220k+ metabolites), MetaboLights, Metabolomics Workbench, and PubChem. Use when asked to identify or annotate metabolites (HMDB IDs, chemical properties, pathways), retrieve metabolomics study information from MetaboLights (MTBLS*) or Metabolomics Workbench (ST*), search for studies by keywords or disease, or generate comprehensive metabolomics research reports.