Design Claude Skills
2 394 design skills from 450 authors. They decide how things look — layout, type and interface behaviour. Half of them fit into 1 928 tokens or less — that is what one costs your context window when the agent loads it. 316 ship runnable scripts rather than instructions alone. 2 of them cannot work without an MCP server, most often rube. We also found 395 copies of these same skills sitting in other people's repositories — counted once here, not 395 times.
2 394 unique 450 authors 1 378 updated this month 195 from vendors
| 当系统提示词需要定义 AI 模型何时搜索、如何搜索、搜索哪些数据源、以及如何处理搜索结果时调用此 Skill。适用于所有涉及实时知识检索的 AI 产品设计——聊天机器人、研究助手、企业知识库问答等。不适用于：纯离线场景（无搜索能力的环境）、已完全内化的知识问答（如数学推导）、创意生成任务。当需求仅涉及"从本地文件读取内容"而非"联网检索外部信息"时，这不是最佳 Skill。
> Audit and fix Beamer slide decks for compilation errors, layout problems, and visual issues. Use this skill whenever the user says "check my slides", "fix my slides", "the slides don't compile", "text is running off the page", "slides look wrong", or after generating a Beamer deck to verify it before delivering. Also use when the user mentions overfull boxes, overlapping content, broken images, or any Beamer formatting issue.
Apply 2026's top graphic design trends to any creative brief. Based on Kittl × Savee's 2026 Design Trends Report (10 trends + 2 honorable mentions), backed by Adobe, Figma, and Pinterest data. Use when: **Designing a brand identity** — pick the right aesthetic for your audience; **Creating social media assets** — use trending visual languages that perform; **Briefing a designer or AI image tool** — give precise style direction with vocabulary and references; **Refreshing a visual identity** — know what's rising vs saturating; **Building mood boards** — combine trends intentionally with data-backed rationale.
> Transform Claude into an expert in evidence-based educational presentation design. Use when designing presentations for teaching, training, or learning contexts where retention and comprehension matter. Applies Cognitive Load Theory, Mayer's 12 Principles of Multimedia Learning, Gagné's 9 Events of Instruction, C.R.A.P. design principles, and WCAG 2.1 AA accessibility standards. Triggers on requests to (1) create educational or training presentations, (2) design slides for teaching or workshops, (3) improve existing educational presentations, (4) convert content into visual presentations, (5) ensure accessible and inclusive presentations, or (6) apply learning science to presentation design.
Create winning RFP/RFI responses by analyzing requirements, structuring compliant proposals, and crafting compelling win themes
Use this skill when you need to design accessibility testing against WCAG, keyboard navigation, and assistive technology scenarios; triggers include accessibility testing and a11y testing.
Use this skill when you need to design accessibility testing against WCAG, keyboard navigation, and assistive technology scenarios; triggers include 可访问性测试 and accessibility testing.
Analyze NPS, CSAT, and qualitative customer feedback to extract themes, identify trends, and generate actionable insight reports.
Audit web interfaces against WCAG 2.1 AA/AAA standards, identify violations, and produce actionable remediation reports with code fixes.
Design and build production-ready frontend interfaces with design systems, responsive layouts, accessible components, and dark mode support.
Design professional, scalable logos with complete brand identity deliverables including color palettes, typography, format variations, and usage guidelines.
Create text-based wireframes at low, mid, and high fidelity with component inventories, interaction annotations, and responsive breakpoint specifications.
Build sales battlecards with feature comparisons, objection handling scripts, positioning statements, and win themes for competitive deal scenarios.
Designer-turned-developer who crafts stunning UI/UX even without design mockups. Use for any frontend implementation requiring visual design decisions, aesthetic direction, or pixel-perfect UI work.
Generates complete modules and components from interface contracts and specifications. Use when Claude needs to build larger software components, implement interfaces, create service layers, or generate complete modules with multiple related classes. Supports Python (with type hints and protocols) and Java (with interfaces and abstract classes). Trigger when users request "implement this interface", "generate a module for", "create a service layer", "build a component that implements", or provide interface definitions that need implementation.
Composes single-file HTML artifacts (PR review writeups, status reports, incident postmortems, slide decks, design systems, prototypes, flowcharts, module maps, feature explainers, kanban boards, prompt tuners) from a small JSON spec instead of hand-written HTML/CSS/JS. Use when the user asks to "compare options side-by-side", requests an HTML version of a report or review or deck, asks for a flowchart, status update, postmortem, design system reference, interactive prototype, custom editor — or explicitly says "HTML artifact", "single HTML file", "self-contained HTML". Skip for ad-hoc HTML snippets (forms, emails, embedded widgets) where there's no template fit.
Design Apple-style iOS/macOS interfaces following Human Interface Guidelines. Creates HIG-compliant components with SF Symbols, San Francisco typography, and proper accessibility. Supports optional modern effects. Use when designing Apple-style UI, iOS/macOS interfaces, HIG-compliant components, or implementing design system specifications.
ATAC-seq processing with assay QC, MACS3 peak calling, consensus peak matrices, differential accessibility, and motif or footprint follow-up.
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.
End-to-end ATAC-seq workflow from FASTQ files to differential accessibility and TF footprinting. Covers alignment, peak calling with MACS3, QC metrics, and optional TOBIAS footprinting. Use when running end-to-end ATAC-seq analysis from FASTQ to differential accessibility.
Designs experiments to minimize and account for batch effects using balanced layouts and blocking strategies. Use when planning multi-batch experiments, assigning samples to sequencing lanes, or designing studies where technical variation could confound biological signals.
Infer cis-regulatory connections (peak-to-peak co-accessibility) from scATAC-seq using Cicero, ArchR getCoAccessibility, or SCENIC+. Use when linking enhancer accessibility to promoter accessibility, identifying enhancer-gene pairs from chromatin alone (without paired RNA), running gene-regulatory inference combining ATAC + RNA, or comparing predicted regulatory contacts against Hi-C/Micro-C ground truth.
Select colormaps and qualitative palettes for scientific figures using perceptual-uniformity, color-vision-deficiency safety, and luminance-monotonicity criteria. Covers Crameri scientific colormaps, viridis/cividis/magma, Okabe-Ito categorical, ColorBrewer, and the rainbow/jet critique. Use when choosing palettes for heatmaps, scatter, networks, or any encoding where color carries quantitative or categorical meaning.
Build a differential-ready consensus peakset from per-replicate ATAC-seq peaks using iterative overlap removal, fixed-width re-centering, and majority-rule overlap. Use when generating a stable peak coordinate system for downstream differential accessibility, ML feature engineering, cross-sample comparison, or fixed-width peak counts; covers Corces 2018 iterative overlap (501 bp), DiffBind summit re-centering, and ENCODE consistency rules.
Identify differentially accessible chromatin regions across conditions using DiffBind, csaw, DESeq2, or edgeR. Use when comparing ATAC-seq accessibility between treatment groups, choosing between consensus-peak vs sliding-window approaches, picking the correct normalization (full library vs reads-in-peaks), correcting batch with SVA/RUVseq, or interpreting log2FC and FDR thresholds in a chromatin context.
Fetch and render web pages using the Servo browser engine — a single binary with JS execution, CSS layout, screenshots, and content extraction. Use when a URL returns empty or incomplete content with plain HTTP fetch, when you need a screenshot without GPU, or when you need to run JavaScript in a page context. No browser download required.
Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Li & Hart 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving 2-3x sensitivity over MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).
Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.
Exports publication-ready figures in various formats with proper resolution, sizing, and typography. Use when preparing figures for journal submission, creating vector graphics for presentations, or ensuring consistent figure styling across analyses.
Designs novel molecules using REINVENT 4 (de novo, scaffold decoration, linker design, R-group, molecular optimization), MolMIM, Diffusion-based generators (DiGress, DiffSMol), and JT-VAE with explicit handling of multi-parameter optimization (MPO), goal-directed scoring functions, transfer/reinforcement/curriculum learning, synthetic accessibility scoring, and chemical space exploration vs exploitation. Use when designing new chemical matter against a target, decorating a scaffold, linking fragments, or optimizing a hit for multiple ADMET / activity properties simultaneously.
Build publication-quality figures in R with ggplot2 using the grammar of graphics (data + aesthetics + geometries + scales + facets + themes) with CVD-safe palettes, cairo_pdf TrueType embedding, programmatic aes via tidy evaluation, and the theme_classic publication baseline. Use when producing static figures in R for papers, presentations, or reports.
Analyze TF motif accessibility variability across samples or single cells using chromVAR. Use when identifying TF motifs whose accessibility correlates with conditions, computing per-sample motif z-scores after matched background correction, comparing to ArchR / Signac equivalents, or distinguishing motif-accessibility signal from per-site footprinting.
Visualize biological networks (PPI, gene-regulatory, co-expression, pathway) with layout algorithm choice (ForceAtlas2, Fruchterman-Reingold, Kamada-Kawai, hive plots), edge bundling, community-based coloring, and reproducible seeds using NetworkX, PyVis, igraph, and Cytoscape automation. Use when rendering biological networks for static publication, interactive HTML exploration, or Cytoscape-format export.
Process and analyze single-cell ATAC-seq data with Signac, ArchR, SnapATAC2, or Cell Ranger ATAC. Use when handling 10X scATAC or 10X Multiome (paired RNA+ATAC) data, performing per-cell QC, choosing between ArchR/Signac/SnapATAC2 ecosystems, building per-cluster consensus peaksets, integrating with paired scRNA-seq, doublet detection (AMULET vs ArchR vs scDblFinder), or running pseudobulk differential accessibility per cluster.
Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes. Use when fetching UniProtKB entries, navigating the JSON schema, choosing between UniProtKB/UniRef/UniParc/Proteomes resources, deciding stream vs search endpoint for batch retrieval, running ID-mapping jobs with the async pattern, handling isoform suffixes, or filtering reviewed Swiss-Prot vs auto-annotated TrEMBL. Encodes the legacy URL migration (2022), the new JSON schema layout, and bulk-pull patterns.
> Predict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA (1) Scoring the regulatory effect of a variant on expression/accessibility, (2) Generating predicted coverage tracks for a locus, (3) Prioritising non-coding variants by predicted track delta.
Summarise pre-computed differential expression results with ranked gene lists, biological themes, and publication-ready interpretation.
> Query the DrugComb drug combination database for cancer cell-line synergy and sensitivity data. Use whenever the user asks about drug combinations, synergy scores (ZIP/Bliss/Loewe/HSA), combination sensitivity (CSS), or wants to look up how two drugs interact in a specific cancer cell line.
Exports any structured experimental data (JSON, tables, time series) to well-formatted Excel (.xlsx) files. Auto-names sheets (Raw Data, Growth Curves, Cell Counts, etc.), adds unit headers and annotation rows, applies consistent styling, and produces lab-ready spreadsheets for sharing, archival, or downstream analysis in R, pandas, or Excel.
> Send rich interactive cards with embedded images in Feishu group chats. Use when reporting progress, sharing analysis results, or presenting any content that benefits from mixed text+image layout in Feishu. Combines SVG UI templates (or matplotlib/PIL charts) with Feishu Card Kit API.
Create publication-quality matplotlib/seaborn charts with readable axes, tight layout, and curated palettes.
Generate SLURM `sbatch` job scripts and sanity-check HPC resource requests (nodes, tasks, CPUs, memory, GPUs) for simulation runs. Use when preparing submission scripts, deciding MPI vs MPI+OpenMP layouts, standardizing `#SBATCH` directives, or debugging job launch configuration (`sbatch`/`srun`).
| Aesthetic guidelines for scientific figure production. Each style file specifies palettes, typography, layout, and domain-specific sub-styles for a given target venue (NeurIPS, Nature, IEEE, etc.) and figure class (methodology diagram vs. statistical plot). Used by the Graph Maker Team's `illustrator` and `data_plotter` agents.
Research posters in LaTeX using beamerposter, tikzposter, or baposter. Layout, typography, color schemes, figure integration, accessibility, and QA for conferences. Includes templates. For figure generation use matplotlib-scientific-plotting or plotly-interactive-visualization.
Migrate a click-ui component from styled-components to CSS Modules with byte-for-byte visual regression coverage. Use whenever a component still uses styled-components and is on the CSS Modules migration list.
Use this skill when the user wants to turn an application, product, startup idea, SaaS, mobile app, web app, API, AI product, or internal tool into a production-ready Markdown specification package for coding agents. Creates PRD/product spec, UX flows, design system brief, technical architecture, ADRs, AI/safety/privacy specs, API/data model, client/backend implementation specs, QA acceptance tests, release readiness, and executable task checklists. Do not use for simple one-off coding tasks unless the user asks for a complete spec, PRD, ADR, project plan for coding agents, or build package.