3 457 productivity skills from 510 authors. They keep notes, tasks, calendars and plans in order. Half of them fit into 1 851 tokens or less — that is what one costs your context window when the agent loads it. 479 ship runnable scripts rather than instructions alone. 51 of them cannot work without an MCP server, most often rube. We also found 336 copies of these same skills sitting in other people's repositories — counted once here, not 336 times.
3 457 unique 510 authors 2 017 updated this month 293 from vendors
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
Evidence-grounded target validation scoring with GO/NO-GO decisions for drug discovery campaigns
Guides structured 4-stage experiment execution with attempt budgets and gate conditions: Stage 1 initial implementation (reproduce baseline), Stage 2 hyperparameter tuning, Stage 3 proposed method validation, Stage 4 ablation study. Integrates with evo-memory (load prior strategies, trigger IVE/ESE) and experiment-craft (5-step diagnostic on failure). Use when: user has a planned experiment, needs to reproduce baselines, organize experiment workflow, or systematically validate a method. Do NOT use for debugging a specific experiment failure (use experiment-craft) or designing which experiments to run (use paper-planning).
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.
Creative research ideation and exploration. Use for open-ended brainstorming sessions, exploring interdisciplinary connections, challenging assumptions, or identifying research gaps. Best for early-stage research planning when you do not have specific observations yet. For formulating testable hypotheses from data use hypothesis-generation.
Run structured What-If scenario analysis with multi-branch possibility exploration. Use this skill when the user asks speculative questions like "what if...", "what would happen if...", "what are the possibilities", "explore scenarios", "scenario analysis", "possibility space", "what could go wrong", "best case / worst case", "risk analysis", "contingency planning", "strategic options", or any question about uncertain futures. Also trigger when the user faces a fork-in-the-road decision, wants to stress-test an idea, or needs to think through consequences before committing.
> CJK (中日韩) 字体检测与 matplotlib 配置。任何涉及中文标签、标题、图例的 可视化任务启动前必须先执行本 skill 的字体检测流程,确保不会出现方块乱码。 适用于 matplotlib / seaborn / plotly 静态导出等场景。
Use this skill whenever the user wants to convert DICOM files or folders to NIfTI format (.nii or .nii.gz), extract neuroimaging volumes from clinical DICOM series (MRI, CT, PET, etc.), prepare raw DICOM data for research processing pipelines, anonymize while converting, or batch-convert multiple series/studies. Triggers include: 'DICOM to NIfTI', 'dcm to nii', 'convert dicom to nii.gz', 'dcm2niix', 'extract nii from dicom', 'batch dicom to nifti', 'prepare dicom for freesurfer/fsl/spm', 'anonymized nifti conversion', or any request to transform clinical DICOM data into analysis-ready NIfTI format while preserving orientation, voxel spacing, slice timing (when available), and important metadata in the JSON sidecar.
Generate reproducible Methods documentation from workflow run artifacts (Nextflow/Snakemake/CWL), including exact commands, versions, parameters, QC gates, and outputs.
Structured, decision-ready review framework for AI/ML, computational biology, and bioscience proposals. Use when evaluating grant, project, or funding proposals.
Plan and evaluate mesh generation for numerical simulations. Use when choosing grid resolution, checking aspect ratios/skewness, estimating mesh quality constraints, or planning adaptive mesh refinement for PDE discretization.
Select and configure time integration methods for ODE/PDE simulations. Use when choosing explicit/implicit schemes, setting error tolerances, adapting time steps, diagnosing integration accuracy, planning IMEX splitting, or handling stiff/non-stiff coupled systems.
Identify computational bottlenecks, analyze scaling behavior, estimate memory requirements, and receive optimization recommendations for any computational simulation. Use when simulations are slow, investigating parallel efficiency, planning resource allocation, or seeking performance improvements through timing analysis, scaling studies, memory profiling, or bottleneck detection.
| Analyzes events through psychological lens using cognitive psychology, social psychology, developmental psychology, clinical psychology, and neuroscience. Provides insights on behavior, cognition, emotion, motivation, group dynamics, decision-making biases, mental health, and individual differences.
Checklist-style reference for OmicVerse downstream tutorials covering AUCell scoring, metacell DEG, and related exports.
Plan and control time-step policies for simulations. Use when coupling CFL/physics limits with adaptive stepping, ramping initial transients, scheduling outputs/checkpoints, or planning restart strategies for long runs.
Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence. Generates quantitative safety signal scores (0-100) with evidence grading. Use for post-market surveillance, pharmacovigilance, drug safety assessment, adverse event investigation, and regulatory decision support.
Strategic clinical trial design feasibility assessment using ToolUniverse. Evaluates patient population sizing, biomarker prevalence, endpoint selection, comparator analysis, safety monitoring, and regulatory pathways. Creates comprehensive feasibility reports with evidence grading, enrollment projections, and trial design recommendations. Use when planning Phase 1/2 trials, assessing trial feasibility, or designing biomarker-driven studies.
Comprehensive drug-drug interaction (DDI) prediction and risk assessment. Analyzes interaction mechanisms (CYP450, transporters, pharmacodynamic), severity classification, clinical evidence grading, and provides management strategies. Supports single drug pairs, polypharmacy analysis (3+ drugs), and alternative drug recommendations. Use when users ask about drug interactions, medication safety, polypharmacy risks, or need DDI assessment for clinical decision support.
Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
Prepare for US medical licensing exams with progress tracking, weak area analysis, question bank management, and residency match planning.
Turn a large task into a persistent plan file and a trackable Issue CSV (local files, not an external issue tracker), then execute the issues autonomously with per-row status updates. Use when work must survive across sessions or hand off between agents, when you need an auditable record of multi-step execution, or to resume a plans/ and issues/ pair from an earlier session. Do not use for single-session tasks that your harness's built-in plan or todo tracking already covers.
Expert culinary professional with advanced skills in food preparation, kitchen operations management, menu engineering, and culinary team leadership. Covers recipe development, technique guidance, flavor troubleshooting, food cost optimization, and HACCP food safety compliance. Use when: cooking, recipe development, menu planning, kitchen management, food safety questions, or culinary team
A skilled executive assistant that helps with calendar management, travel coordination, and comprehensive executive support. Streamlines scheduling, drafts communications, and manages complex logistics so executives can focus on high-value decisions. Use when: working with executive-assistant.
Expert driver with advanced skills in safe vehicle operation, route optimization, defensive driving, and fleet vehicle maintenance. Use when working on trip planning, driving safety, vehicle care, or transportation logistics. Use when: working with driver.
Flight test engineer specializing in test planning, flight operations, data acquisition, and certification validation for aircraft development programs.
Satellite systems engineer specializing in spacecraft design, orbital mechanics, payload integration, and mission operations planning.
Expert-level Vertiport Planning Engineer specializing in vertiport site selection, FATO/TLOF design, passenger terminal layout, charging infrastructure, capacity modeling, fire protection (FAA AC 150/5390-2D equivalent), noise compatibility, building... Use when: vertiport, ua...
Expert agricultural data scientist with 12+ years in precision agriculture, remote sensing, and farm analytics. Specializes in yield prediction, variable rate application, satellite imagery analysis, and decision support systems. Use when: precision-agriculture, remote-sensing, yield-prediction, ag-analytics, farm-data.
Expert forestry engineer with 15+ years in afforestation planning, forest resource management, timber harvest operations, and ecosystem restoration. Specializes in species-site matching, sustainable harvest planning, and carbon project development. Use when: forestry, afforestation, forest-management, timber, ecosystem-restoration.
Expert machine learning engineer skill. Use when: machine learning engineer tasks, machine learning engineer deliverables, machine learning engineer decisions.
Expert-level Autonomous Driving Engineer with deep knowledge of full ADAS stack (L1-L5), perception (camera/LiDAR/radar fusion), path planning (RRT*, MPC, behavior planning), HD map integration, safety validation (ISO 26262, SOTIF), and open platforms... Use when: autonomous-d...
Expert-level Planning & Decision Engineer specializing in trajectory planning, behavior prediction, decision algorithms, and motion planning for autonomous vehicles
Expert-level Operations Manager skill covering process optimization, supply chain management, lean operations, KPI management, and operational excellence. Use when: operations, process-optimization, lean, supply-chain, operational-excellence, workflow-design.
Expert-level Strategy Consultant skill covering corporate strategy, competitive analysis, market entry, portfolio strategy, M&A, and growth planning
Expert-level Project Manager skill covering project planning, risk management, stakeholder alignment, agile/scrum delivery, budget management, and cross-functional team leadership
Certified crane operator with 10+ years experience in tower cranes, mobile cranes, and overhead cranes. Specializes in load calculation, lift planning,rigging, and OSHA-compliant safety protocols
Licensed Architect (AIA, LEED AP BD+C) with 15+ years designing commercial, institutional, and residential projects. Expert in schematic design, design development, construction documentation, and contract administration. Licensed in 8 states with $500M+ in constructed projects. Use when: architecture, building design, space planning, code compliance, sustainable design, construction documents.
Senior construction manager (CM) with PMP, CCM, and LEED AP credentials. Expert in project planning, scheduling, subcontractor coordination, safety compliance, and cost control. Manures $50M+ commercial projects with 15+ years field experience. Use when: construction management, project planning, site coordination, schedule control, subcontractor management.
A world-class interior designer specializing in residential and commercial interior spaces, material selection, lighting design, and space planning
Chartered Quantity Surveyor (MRICS) with 15+ years in construction cost management, contract administration, and value engineering. Expert in cost planning, tender documentation, post-contract administration, and dispute resolution. Managed $2B+ in construction value across commercial, infrastructure, and residential projects. Use when: cost estimating, quantity surveying, contract
Expert jewelry designer creating original designs from concept to finished piece. Use when designing custom jewelry, selecting gemstones, planning manufacturing processes, or selecting materials
Expert animator with 12+ years in 2D/3D animation, motion graphics, and visual effects for film, TV, and digital media. Specializes in character animation, timing and spacing, squash and stretch, and production workflows. Use when: animation, motion-graphics, visual-effects, 2d-animation, 3d-animation.
Expert Career Counselor specializing in career development theory, vocational assessment, job search strategy, and professional identity formation. Expert in Holland Codes, StrengthsFinder, and labor market analysis for educational and career planning. Use when: career-counseling, vocational-guidance, job-search, career-development, strengths-assessment, career-transition.
A world-class K-12 teacher specializing in curriculum design, student assessment, differentiated instruction, and classroom management. Expert in Common Core, NGSS, UDL principles, and evidence-based pedagogical practices. Use when: education, teaching, k12, curriculum, assessment, lesson-planning, classroom-management.
Expert School Administrator specializing in educational leadership, school operations, policy implementation, and instructional supervision. Expert in school improvement planning, staff evaluation, budget management, and community engagement. Use when: school-administration, educational-leadership, principal, school-improvement, staff-evaluation, school-operations.