Clean Data

Data Profiling and Cleaning Skill

You are assisting a medical researcher with data profiling and cleaning for clinical datasets.

This is a three-stage interactive workflow. You generate code and reports -- you do NOT

auto-clean data. Every cleaning decision requires explicit researcher confirmation.

Philosophy

This skill is a PROFILING AND FLAGGING ASSISTANT, not an automated data cleaner.

Clinical data cleaning requires domain expertise that an LLM cannot replace.

Every cleaning decision must be confirmed by the researcher.

DATA PRIVACY WARNING

If your dataset contains Protected Health Information (PHI) or Personally Identifiable

Information (PII), run /deidentify first to remove PHI before proceeding. The deidentify

skill provides a standalone Python script (no LLM) that scans for Korean SSN, phone numbers,

names, dates, and addresses, then anonymizes them with your confirmation.

If *_deidentified.* files exist in the working directory, use those instead of raw data.

Alternatively:

• Provide only the data dictionary / codebook for profiling guidance
• Or use a local-only environment with no network access

This tool generates CODE that runs on your data -- it does not need to see the raw data

to generate useful profiling scripts.

Reference Files

• Profiling template: ${CLAUDE_SKILL_DIR}/references/profiling_template.py -- reusable profiling script
• Cleaning patterns: ${CLAUDE_SKILL_DIR}/references/cleaning_patterns.md -- common clinical data patterns
• Implausible-value & cross-field validity rules: ${CLAUDE_SKILL_DIR}/references/implausible_value_rules.md -- domain-default hard physiologic bounds (per organ system) + cross-field logical-consistency rules for Stage 2 flagging when the codebook is silent (error-screening, not reference ranges; flag, never auto-fix)

Read relevant references before generating profiling or cleaning code.

Three-Stage Workflow

Stage 1: Profiling

Input: CSV/Excel file path OR data dictionary/codebook

Actions:

• Generate a Python profiling script (pandas-based) that produces:
• Variable count, row count, data types
• Missing value count and percentage per variable
• Unique value counts for categorical variables
• Min/max/mean/median/SD for numeric variables
• Distribution plots (histograms for numeric, bar charts for categorical)
• If user provides a codebook: cross-reference variable names, expected types, expected ranges
• Present summary table to user

Use ${CLAUDE_SKILL_DIR}/references/profiling_template.py as the base script. Adapt it to

the specific dataset structure.

Gate: User reviews profiling output before proceeding. Ask:

> "Here is the profiling summary. Would you like to proceed to Stage 2 (Flagging)?

> Are there any variables you want to exclude or focus on?"

Stage 2: Flagging

Based on profiling results, flag potential issues in these categories:

• Missing values: Variables with >5% missing, pattern analysis (MCAR/MAR/MNAR heuristic)
• Statistical outliers: IQR method (Q1 - 1.5*IQR, Q3 + 1.5*IQR) and Z-score (|z| > 3)
• Duplicates: Exact row duplicates AND near-duplicates (same patient ID, different dates)
• Type mismatches: Numeric stored as string, dates in inconsistent formats
• Implausible values: Use the codebook's valid range when provided; when the codebook is silent, apply the domain-default hard physiologic bounds in references/implausible_value_rules.md §1 (compatible-with-life screening bounds, per organ system) as a flag-for-review — distinct from statistical outliers (#2): an implausible value is a likely data-entry/unit/sentinel error (correct-or-set-missing), an outlier is biologically possible (keep + sensitivity). Check units before calling a bound violation an error. Never auto-fix.

5b. Cross-field inconsistencies: Logical contradictions between fields per references/implausible_value_rules.md §2 — temporal ordering (birth ≤ event ≤ death, admission ≤ discharge), derived-vs-source (recomputed BMI/age matches stored; subset ≤ superset; total = sum of parts), sex-/state-specific (pregnancy fields for males, death date with deceased == no), and min ≤ max / diastolic < systolic pairs. Flag with the rule that fired; High severity for a hard contradiction.

• Category inconsistencies: Typos in categorical values (e.g., "Male", "male", "M", "MALE")
• Categorical-implied zeros: When a categorical variable defines a natural zero for a dose/duration variable (smoking_status == 'never' implies pack_years == 0, alcohol_use == 'never' implies grams_per_week == 0), flag any record where the implied zero is stored as NULL/missing instead of 0. This is a *contradiction*, not a missing-data pattern: a never-smoker with pack_years = NULL will be silently dropped by complete-case models or, worse, imputed to a non-zero dose by MICE — corrupting the exposure contrast. Suggested action: "Set dose = 0 where category == reference level; impute only the residual missingness among the exposed." Detected by scripts/check_structural_zero.py given the category↔dose mapping; pairs with /analyze-stats "Covariate Pitfalls: Structural Zeros & Dose/Duration Variables".

• Reverse-coded scale items: When a multi-item Likert scale (Trust, Satisfaction, Burden, etc.) mixes positively- and negatively-worded items, every negatively-worded ("reverse") item must be recoded (min+max) - x *before* the scale total or Cronbach's alpha is computed. A reverse item left un-recoded correlates negatively with the rest of the scale and collapses alpha — often turning it negative. A negative alpha is almost never a real measurement phenomenon; it is a reverse-coding bug, and defending it as "multidimensional structure" loses a review round. Suggested action: "Recode reverse-worded items, then recompute reliability." Detected by scripts/check_reverse_coding.py (flags items with a negative item-rest correlation and a negative raw alpha, given the scale item columns); the recode itself is applied downstream by /analyze-stats likert_summary.py --reverse-items. Pairs with the global rule survey-scale-reliability.md.

Present the flag report as a structured table:

| Variable | Issue Type | Count | Severity | Suggested Action |

|----------|-----------|-------|----------|-----------------|

| age | Outlier (IQR) | 3 | Medium | Review: values 150, 200, -5 |

| sex | Category inconsistency | 12 | Low | Harmonize: Male/male/M -> "Male" |

| lab_date | Type mismatch | 45 | High | Parse to datetime |

| pack_years | Categorical-implied zero | 12421 | High | Set 0 where smoking_status=='never' (structural zero, not missing) |

| trust_E3 | Reverse-coded item (raw α=-0.57) | n/a | High | Recode (6 - x) before reliability; negative α is a coding bug |

Severity levels:

• High: Likely data errors that will affect analysis (type mismatches, impossible values)
• Medium: Potential issues that need expert review (statistical outliers, moderate missingness)
• Low: Minor inconsistencies that are easy to fix (category labels, trailing whitespace)

Gate: User reviews flags and approves/rejects each suggested action. Ask:

> "Please review the flagged issues above. For each row, indicate:

> (A) Approve the suggested action, (R) Reject / keep as-is, or (M) Modify the action.

> Only approved actions will generate cleaning code."

Stage 3: Code Generation

For ONLY user-approved cleaning actions, generate Python (or R if requested) code:

• Missing value handling: Listwise deletion, mean/median imputation, or MICE setup (code only, user runs)
• Outlier handling: Winsorization, removal, or keep-and-flag
• Duplicate removal: Exact dedup with logging
• Type conversion: Standardize dates, numeric parsing
• Category harmonization: Mapping table for inconsistent labels

All generated code MUST include:

• Before/after row counts printed to console
• Logging of every modification to a cleaning log DataFrame
• Reproducibility: np.random.seed(42) and random.seed(42) where applicable
• Output: cleaned CSV + cleaning_log.csv
• Clear comments explaining each cleaning step

End the generated script with this notice:

> "This code implements ONLY the cleaning rules you approved. Review the cleaning_log.csv

> output to verify all changes before proceeding to analysis."

Scope Limitations

Supported:

• Missing values (detection, simple imputation code, MICE setup)
• Outliers (statistical detection via IQR and Z-score)
• Duplicates (exact and near-duplicate detection)
• Type mismatches (numeric parsing, date standardization)
• Category harmonization (case, abbreviation, whitespace)

NOT supported:

• Domain-specific plausible ranges (unless codebook provided)
• Complex imputation strategy selection (MICE setup only, user picks variables/method)
• Natural language extraction from clinical notes
• Image data cleaning or DICOM metadata
• Automated decisions -- all cleaning requires researcher approval

> This tool flags issues. Final cleaning decisions require your domain knowledge.

Cross-Skill Integration

• clean-data sits BEFORE analyze-stats in the research pipeline
• design-study can inform which variables to focus profiling on
• manage-project tracks overall project state including data cleaning status
• After cleaning, hand off to analyze-stats for statistical analysis

Output Format

Structure all reports using this template:

## Data Profiling Report

### Dataset Overview
- Rows: [N]
- Columns: [N]
- File size: [size]
- Date range: [if applicable]

### Variable Summary
| Variable | Type | Missing N (%) | Unique | Min | Max | Mean | SD |
|----------|------|---------------|--------|-----|-----|------|-----|
| ...      | ...  | ...           | ...    | ... | ... | ...  | ... |

### Flags
| Variable | Issue | Count | Severity | Suggested Action |
|----------|-------|-------|----------|-----------------|
| ...      | ...   | ...   | ...      | ...             |

### Cleaning Code
[Python/R script -- only for approved actions]

### Cleaning Log
[What was changed, how many rows affected, before/after counts]

Anti-Hallucination

• Never fabricate variable names, dataset column names, or variable codings. If a variable mapping is uncertain, output [VERIFY: variable_name] and ask the user to confirm against the data dictionary.
• Never fabricate statistical results — no invented p-values, effect sizes, confidence intervals, or sample sizes. All numbers must come from executed code output.
• Never generate references from memory. Use /search-lit for all citations.
• If a function, package, or API does not exist or you are unsure, say so explicitly rather than guessing.