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Opentargets MCP Server

local only

Opentargets runs on your own machine — the client starts it, so there is no endpoint to ping. 110 installs a week from pypi. Last commit 15 May 2026.

Open Targets MCP server for targets, diseases, drugs, variants, and evidence

Installs per day peak 36 · avg 13 · +25% w/w
a month agotoday
110
Installs / week
pypi · opentargets-mcp
19
Stars
0 open issues
15 May 2026
Last commit
0 releases in 90 days
MIT
License
Python

Nothing serious here today

Today is the operative word: we check Opentargets every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.

Three servers free · no card

Connect this server

This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.

run in your terminal
claude mcp add opentargets -- uvx opentargets-mcp
~/Library/Application Support/Claude/claude_desktop_config.json
{
  "mcpServers": {
    "opentargets": {
      "args": [
        "opentargets-mcp"
      ],
      "command": "uvx"
    }
  }
}
~/.codex/config.toml
[mcp_servers.opentargets]
command = "uvx"
args = ["opentargets-mcp"]
.cursor/mcp.json
{
  "mcpServers": {
    "opentargets": {
      "args": [
        "opentargets-mcp"
      ],
      "command": "uvx"
    }
  }
}
.vscode/mcp.json
{
  "mcpServers": {
    "opentargets": {
      "args": [
        "opentargets-mcp"
      ],
      "command": "uvx"
    }
  }
}

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Opentargets — questions

Answers built from our own checks of this server.

Why is there no uptime for Opentargets?
Opentargets runs on your own machine over stdio — there is no network address to reach, so uptime cannot be measured for it by anyone. What can be measured is adoption: the pypi package opentargets-mcp was installed 110 times last week.
How do I connect Opentargets?
Copy the ready config from this page — we generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each with the file path that client actually reads. It runs locally, so the command pulls opentargets-mcp straight from pypi; nothing to host, nothing to sign up for.
How many people use Opentargets?
The pypi package opentargets-mcp was installed 110 times in the last week. Week over week that is +25%. We show installs rather than GitHub stars on purpose: a star is a bookmark, an install is someone actually running it.
Is Opentargets open source?
Yes — it is published under the MIT licence, written in Python and 19 stars on GitHub. The source link is on this page, so you can read exactly what it does with your data before you connect it.