Hpo MCP runs on your own machine — the client starts it, so there is no endpoint to ping. 496 installs a week from npm. Last commit 28 Oct 2026.
Search HPO phenotype terms, read definitions and explore the phenotype hierarchy - keyless.
Today is the operative word: we check Hpo MCP every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.
This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.
claude mcp add hpo-mcp -- npx -y @mrfentmen/hpo-mcp
{
"mcpServers": {
"hpo-mcp": {
"command": "npx",
"args": [
"-y",
"@mrfentmen/hpo-mcp"
]
}
}
}
[mcp_servers.hpo-mcp]
command = "npx"
args = ["-y", "@mrfentmen/hpo-mcp"]
{
"mcpServers": {
"hpo-mcp": {
"command": "npx",
"args": [
"-y",
"@mrfentmen/hpo-mcp"
]
}
}
}
{
"servers": {
"hpo-mcp": {
"type": "stdio",
"command": "npx",
"args": [
"-y",
"@mrfentmen/hpo-mcp"
]
}
}
}
Gene Ontology terms, definitions, hierarchy and protein annotations via EBI QuickGO - keyless.
Search and read terms across hundreds of biomedical ontologies via the EBI OLS - keyless.
Search the SwaggerHub API registry for public API definitions. No key required.
Search the Library of Congress catalogue, collections and digitised items - keyless.
InterPro protein families and domains: search entries and find the domains in one protein - keyless.
MITRE CWE weakness records: descriptions, mitigations, consequences and the weakness hierarchy.
Search KEGG genes and compounds, read entries and list their pathways - keyless.
Read a CFR or eCFR section, or search US federal regulations and the Federal Register.
Answers built from our own checks of this server.