When provisioning, setting a limit, or committing an estimate under uncertainty, size a buffer to residual error and the cost of breach—not to the optimistic edge.
npx skills add https://github.com/tjboudreaux/cc-thinking-skills --skill thinking-margin-of-safety
Core rule: commit a buffered number when residual uncertainty plus breach cost can cause ruin or costly failure. Margin covers estimation error; it is not free slack for laziness.
cost(buffer) > P(breach) × cost(breach)—right-size or measure instead of maxing outCap or cut when buffer cost exceeds expected breach cost.
Base estimate: … (units, confidence)
Uncertainty drivers: …
Breach cost / failure threshold: …
Margin applied: …× (or absolute buffer …)
Buffered commitment: …
Ruin check: pass | redesign needed
Cost of margin vs expected breach cost: …
Monitor: metric … ; thin if … ; excessive if …
Integration with protocols.io API for managing scientific protocols. This skill should be used when working with protocols.io to search, create, update, or publish protocols; manage protocol steps and materials; handle discussions and comments; organize workspaces; upload and manage files; or integrate protocols.io functionality into workflows. Applicable for protocol discovery, collaborative protocol development, experiment tracking, lab protocol management, and scientific documentation.
Analyzes job descriptions and generates tailored resumes that highlight relevant experience, skills, and achievements to maximize interview chances
Generate Excalidraw diagrams from natural language descriptions. Use when asked to "create a diagram", "make a flowchart", "visualize a process", "draw a system architecture", "create a mind map", or "generate an Excalidraw file". Supports flowcharts, relationship diagrams, mind maps, and system architecture diagrams. Outputs .excalidraw JSON files that can be opened directly in Excalidraw.
Build and distribute Expo development clients locally or via TestFlight
Use when you have a written implementation plan to execute in a separate session with review checkpoints
Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.
Take tjboudreaux/thinking-margin-of-safety from the repository into ~/.claude/skills for personal
use, or into .claude/skills inside a project.
The agent identifies a skill by the name field in its header. Two skills with the
same name cannot sit side by side — one of them will be ignored.