Claude Skills
The open format is called Agent Skills and works in Claude Code, Codex, Cursor and other agents — most people know it as Claude Skills.
Every Agent Skill we could find on GitHub, deduplicated by content. 79 437 files from 1 744 authors, of which 61 785 are unique — the rest is the same skill repackaged into someone else's repository. For each one: what it weighs in tokens, whether it ships runnable scripts, and which MCP servers it needs.
Reference — all 20 Xcode MCP tools with parameters, return schemas, and examples
Xcode MCP setup — enable mcpbridge, per-client config, permission handling, multi-Xcode targeting, troubleshooting
Xcode MCP workflow patterns — BuildFix loop, TestFix loop, preview verification, window targeting, tool gotchas
Use when connecting to Xcode via MCP, using xcrun mcpbridge, or working with ANY Xcode MCP tool (XcodeRead, BuildProject, RunTests, RenderPreview). Covers setup, tool reference, workflow patterns, troubleshooting.
Use when writing, running, or debugging XCUITests. Covers element queries, waiting strategies, accessibility identifiers, test plans, and CI/CD test execution patterns.
Use when automating Instruments profiling, running headless performance analysis, or integrating profiling into CI/CD - comprehensive xctrace CLI reference with record/export patterns
CoreML diagnostics - model load failures, slow inference, memory issues, compression accuracy loss, compute unit problems, conversion errors.
CoreML API reference - MLModel lifecycle, MLTensor operations, coremltools conversion, compression APIs, state management, compute device availability, performance profiling.
Use when deploying custom ML models on-device, converting PyTorch models, compressing models, implementing LLM inference, or optimizing CoreML performance. Covers model conversion, compression, stateful models, KV-cache, multi-function models, MLTensor.
Use when implementing speech-to-text, live transcription, or audio transcription. Covers SpeechAnalyzer (iOS 26+), SpeechTranscriber, volatile/finalized results, AssetInventory model management, audio format handling.
Create a new skill in the current repository. Use when the user wants to create/add a new skill, or mentions creating a skill from scratch. This skill follows the workflow defined in .agents/skills/README.md and helps scaffold, validate, and sync new skills.
Use when user wants to create a GitHub issue for the current repository. Must read and follow the repository's issue template format.
Create or update GitHub pull requests using the repository-required workflow and template compliance. Use when asked to create/open/update a PR so the assistant reads `.github/pull_request_template.md`, fills every template section, preserves markdown structure exactly, and marks missing data as N/A or None instead of skipping sections.
Automated code review for local branches, PRs, commits, and files. Supports single-agent review with interactive fix selection, or multi-agent deep review with reviewer-verifier adversarial mechanism and risk-based auto-fix.
Prepare a new release by collecting commits, generating bilingual release notes, updating version files, and creating a release branch with PR. Use when asked to prepare/create a release, bump version, or run `/prepare-release`.
React and Next.js performance optimization guidelines from Vercel Engineering. This skill should be used when writing, reviewing, or refactoring React/Next.js code to ensure optimal performance patterns. Triggers on tasks involving React components, Next.js pages, data fetching, bundle optimization, or performance improvements.
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
Bioconductor package discovery, workflow recommendation, setup inspection, and starter code generation grounded in official Bioconductor containers and BiocManager.
Ancestry decomposition PCA against the Simons Genome Diversity Project
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
Semantic Similarity Index for disease research literature using PubMedBERT embeddings
Find clinical trials for a gene, variant, or condition from ClinicalTrials.gov + EUCTR, with FHIR R4 output
Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels
Extract numerical data from scientific figure images using Claude vision + OpenCV calibration. Supports 26+ plot types including bar charts, scatter plots, forest plots, Kaplan-Meier curves, box plots, and more.
Rich downstream visualisation and reporting for bulk RNA-seq differential expression and scRNA marker/contrast outputs.
Medication photo to personalised PGx dosage card via Claude vision — snap a pill, get genotype-informed guidance
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.
Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org with multi-signal scoring and workflow suggestions
Compare your genome to George Church (PGP-1) and estimate ancestry composition via IBS and EM admixture
Score genetic compatibility across all male-female pairings in a Genomebook generation
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
Calculate polygenic risk scores from DTC genetic data using the PGS Catalog
Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis and downstream routing.
Interact with the Labstep electronic lab notebook API using labstepPy. Query experiments, protocols, resources, inventory, and other lab entities.
Search PubMed and bioRxiv, summarise papers with LLM, build citation graphs, and generate literature review sections.
Compute epigenetic age from DNA methylation arrays using PyAging clocks from GEO accessions or local files.
Personalised nutrition report from consumer genetic data (23andMe, AncestryDNA, VCF) — interrogates nutritionally-relevant SNPs and generates actionable dietary guidance, all computed locally.
Aggregate public target-level evidence across omics and translational sources for research triage.
Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs
>- Unified personal genomic profile report — reads a PatientProfile JSON and synthesizes all skill results into a single "Your Genomic Profile" document.
Differential expression analysis for label-free quantitative (LFQ) intensity data with standard MaxQuant and DIA-NN output. Workflow includes preprocessing, imputation, and statistical testing.
>- Search, browse, and retrieve scientific protocols from protocols.io via REST API. Client token authentication for private protocols. Use when user mentions protocols.io, lab protocols, DOI lookup, protocol search, protocol steps, or scientific methods.
>- Search PubMed for a gene name or disease term and generate a structured research briefing of the top recent English-language papers.
Produce offspring genomes from parent pairs via meiotic recombination, mutation, and clinical evaluation
Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline.
Differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices with QC, PCA, and contrast testing.
Local scVI-based single-cell latent embedding and batch-aware integration from raw-count .h5ad or 10x Matrix Market input, with stable integrated AnnData export for downstream latent analysis.
Local Scanpy pipeline for single-cell RNA-seq QC, optional doublet detection, clustering, marker discovery, optional CellTypist annotation, optional latent downstream mode from integrated.h5ad/X_scvi, and optional two-group contrastive marker analysis from raw-count .h5ad or 10x Matrix Market input.
Sequence QC, alignment, and BAM processing. Wraps FastQC, BWA/Bowtie2, SAMtools for automated read-to-BAM pipelines.
Compile SOUL.md character profiles into synthetic diploid genomes (.genome.json) via trait-to-allele mapping
Local protein structure prediction with AlphaFold, Boltz, or Chai. Compare predicted structures, compute RMSD, visualise 3D models.
Evidence-grounded target validation scoring with GO/NO-GO decisions for drug discovery campaigns
Semantic search across UK Biobank's 12,000+ data fields and publications — find the right variables for your research question.
Annotate VCF variants with Ensembl VEP REST, ClinVar significance, gnomAD/population frequency context, and prioritized variant ranking.
Annotate VCF variants with VEP, ClinVar, gnomAD frequencies, and ancestry-aware context. Generates prioritised variant reports.
MUST USE when reviewing ClickHouse schemas, queries, or configurations. Contains 28 rules that MUST be checked before providing recommendations. Always read relevant rule files and cite specific rules in responses.
Analyzes codebases to understand structure, tech stack, patterns, and conventions. Use when onboarding to a new project, exploring unfamiliar code, or when asked "how does this work?" or "what's the architecture?
Convex backend development guidelines. Use when writing Convex functions, schemas, queries, mutations, actions, or any backend code in a Convex project. Triggers on tasks involving Convex database operations, real-time subscriptions, file storage, or serverless functions.
Designs database schemas, indexing strategies, query optimization, and migration patterns for SQL and NoSQL databases. Use when designing tables, optimizing queries, fixing N+1 problems, planning migrations, or when asked about database performance, normalization, ORMs, or data modeling.
Designs REST and GraphQL APIs including endpoints, error handling, versioning, and documentation. Use when creating new APIs, designing endpoints, reviewing API contracts, or when asked about REST, GraphQL, or API patterns.
Claude Skills — questions
Answers built from the skills we actually parsed.