Claude Skills
The open format is called Agent Skills and works in Claude Code, Codex, Cursor and other agents — most people know it as Claude Skills.
Every Agent Skill we could find on GitHub, deduplicated by content. 79 404 files from 1 741 authors, of which 61 763 are unique — the rest is the same skill repackaged into someone else's repository. For each one: what it weighs in tokens, whether it ships runnable scripts, and which MCP servers it needs.
Submit compact Bgee SPARQL requests for healthy wild-type expression metadata and ontology-aware lookup patterns. Use when a user wants concise Bgee summaries; save raw results only on request.
Submit compact BindingDB REST API requests for ligand-target binding lookups by PDB, UniProt, or similarity search. Use when a user wants concise BindingDB summaries; save raw payloads only on request.
Submit compact bioRxiv and medRxiv API requests for details, publication-linkage, and DOI lookups. Use when a user wants concise preprint metadata summaries
Fetch compact BioBank Japan PheWAS summaries for single variants by accepting rsID, GRCh38, or GRCh37 input and resolving to the required GRCh37 query. Use when a user wants concise BBJ association results for one variant
Submit compact BioStudies and ArrayExpress API requests for free-text search and accession-based study retrieval. Use when a user wants concise BioStudies summaries
Submit compact CELLxGENE Discover API requests for public collection and dataset metadata. Use when a user wants concise single-cell collection summaries
Submit compact cBioPortal API requests for studies, molecular profiles, mutations, clinical data, and samples. Use when a user wants concise cBioPortal summaries
Submit compact ChEMBL API requests for activity, molecule, target, mechanism, and text-search endpoints. Use when a user wants concise ChEMBL summaries
Submit compact ChEBI 2.0 API requests for chemical search, compound lookup, ontology traversal, and structure metadata. Use when a user wants concise ChEBI summaries
Submit compact CIViC GraphQL requests for cancer variant interpretation schema inspection and targeted evidence retrieval. Use when a user wants concise CIViC summaries
Submit compact ClinVar Clinical Tables and NCBI Variation requests for search, VCV, RCV, SCV, and RefSNP lookups. Use when a user wants variant-level summaries or identifier mapping
Submit compact ClinicalTrials.gov API v2 requests for study search, metadata, enums, search areas, and field statistics. Use when a user wants concise ClinicalTrials.gov summaries
Submit compact EFO OLS4 requests for search, term lookup, children, and descendants. Use when a user wants concise EFO resolution or ontology-expansion summaries
Submit compact ENCODE REST API requests for object lookups, portal-style search, and metadata retrieval. Use when a user wants concise ENCODE summaries
Submit compact Ensembl REST API requests for lookup, overlap, cross-reference, and variation endpoints. Use when a user wants concise Ensembl summaries
Submit compact EpiGraphDB API requests for ontology, literature, MR, gene-drug, and support-path evidence. Use when a user wants concise EpiGraphDB summaries
Submit compact eQTL Catalogue API requests for association retrieval and documented metadata endpoints. Use when a user wants concise public eQTL Catalogue summaries
Submit compact EVA REST requests for species metadata and archived variant lookups. Use when a user wants concise European Variation Archive summaries
Submit compact gnomAD GraphQL requests for frequency, gene constraint, and variant context queries. Use when a user wants concise gnomAD summaries
Fetch GTEx single-tissue eQTL associations from one variant input by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query for the GTEx v2 API. Use when a user wants eQTL associations returned as JSON.
Submit compact GWAS Catalog REST API v2 requests for studies, associations, SNPs, EFO traits, genes, publications, loci, and metadata. Use when a user wants concise GWAS Catalog summaries
Submit compact Genebass gene burden requests for one Ensembl gene ID and one burden set. Use when a user wants concise Genebass PheWAS summaries
Fetch compact FinnGen PheWAS summaries for single variants by accepting rsID, GRCh37, or GRCh38 input and resolving to the required GRCh38 query. Use when a user wants concise FinnGen association results for one variant
Submit compact Human Protein Atlas requests for gene JSON, search downloads, and page-level tissue or cell-line lookups. Use when a user wants concise Human Protein Atlas summaries; save raw JSON or HTML only on request.
Submit compact MetaboLights requests for study discovery and study-level metabolomics metadata. Use when a user wants concise MetaboLights summaries
Submit compact MGnify API requests for microbiome studies, samples, and biome metadata. Use when a user wants concise MGnify summaries
Submit compact Clinical Tables NCBI Gene requests for human gene lookup, pagination, and field selection. Use when a user wants concise autocomplete-style human gene search results
Submit, poll, and summarize NCBI BLAST Common URL API jobs (Blast.cgi) for nucleotide or protein sequences. Use when a user wants RID status, BLAST results, or compact top-hit summaries; fetch raw Text/JSON2 only on request.
Submit compact NCBI Datasets v2 requests for assembly, genome, taxonomy, and related metadata endpoints. Use when a user wants concise NCBI Datasets summaries; save raw JSON or text only on request.
Submit compact NCBI Entrez E-Utilities requests for PubMed, Gene, Protein, Nucleotide, PMC metadata, and GEO metadata workflows. Use when a user wants concise Entrez search, fetch, summary, or link results; save raw JSON or XML only on request.
Submit compact HMDB search requests for metabolites, proteins, diseases, and pathways. Use when a user wants concise HMDB summaries
Submit compact Open Targets Platform GraphQL requests for target, disease, drug, variant, study, and search data, including associated-disease datasource heatmap matrices. Use when a user wants concise Open Targets summaries or per-datasource evidence context
Submit compact NCBI PMC Open Access requests for article/file availability metadata. Use when a user wants concise PMC Open Access summaries; save raw XML only on request.
Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO -> GWAS -> coordinates -> Open Targets L2G/coloc -> eQTL -> burden/coding context), with reproducible tables and optional figures. Use when a user provides a trait/EFO term and/or lead variants and needs locus-to-gene prioritization for downstream biology decisions.
Submit compact IPD REST requests for HLA allele and cell-level metadata using the public IPD query API. Use when a user wants concise IPD summaries; save raw JSON or text only on request.
Submit compact PharmGKB API requests for genes, variants, clinical annotations, dosing guidelines, and search. Use when a user wants concise PharmGKB summaries
Submit compact PRIDE Archive API requests for proteomics project discovery and project-level metadata. Use when a user wants concise PRIDE summaries
Submit compact ProteomeXchange PROXI requests for datasets, libraries, peptidoforms, proteins, PSMs, spectra, and USI examples. Use when a user wants concise PROXI summaries
Submit compact PubChem PUG REST requests for compound properties, descriptions, assay summaries, and substance metadata. Use when a user wants concise PubChem summaries
Submit compact QuickGO requests for GO terms, annotations, and ontology traversal. Use when a user wants concise QuickGO summaries
Create new skills, modify and improve existing skills, and measure skill performance. Enhanced version with quick commands. Use when users want to create a skill from scratch, update or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or optimize a skill's description for better triggering accuracy. Triggers on phrases like "make a skill", "create a new skill", "build a skill for", "improve this skill", "optimize my skill", "test my skill", "turn this into a skill", "skill description optimization", or "help me create a skill".
Configure MCP (Model Context Protocol) servers for Claude Code. Manage MCP servers at user or project scope with best practices to avoid context pollution.
Configure VSCode with httpYac for API testing and automation. This skill should be used specifically when converting API documentation to executable .http files (10+ endpoints), setting up authentication flows with pre-request scripts, implementing request chaining with response data, organizing multi-file collections with environment management, or establishing Git-based API testing workflows with CI/CD integration.
This skill should be used when configuring VS Code Port Monitor extension for development server monitoring. Use when the user asks to "set up port monitoring for Vite", "monitor my dev server ports", "configure port monitor for Next.js", "track which ports are running", "set up multi-port monitoring", "monitor frontend and backend ports", or "check port status in VS Code". Provides ready-to-use configuration templates for Vite (5173), Next.js (3000), and microservices architectures with troubleshooting guidance.
This skill should be used when setting up SFTP deployment for static websites to production servers, including converting projects from Docker/Express to static hosting, deploying Vue/React/Angular builds, setting up Slidev presentations, or configuring Hugo/Jekyll/Gatsby sites. Use this when the user asks to "setup SFTP deployment", "deploy static site to server", "configure Nginx for static files", "convert from Docker to static hosting", "deploy Vue build to production", "setup subdomain hosting", or "configure SFTP in VS Code". Provides SFTP configuration templates and production-ready Nginx configurations with security headers and caching.
发布内容和文章到 X (Twitter)。支持常规推文(文字/图片/视频)和 X Articles(长文 Markdown)。使用真实 Chrome 浏览器绕过反机器人检测。当用户说"发推"、"发到 X"、"发到 twitter"、"分享到 X"、"分享到 twitter"、"发 tweet"、"同步到 X"、"发布到 X"、提到"X Articles"、想从 Obsidian 笔记发布长文内容、或需要转换 Obsidian Markdown 到 X 格式时使用。适用于所有 X/Twitter 发布任务。
Author and review GitHub Actions workflow YAML safely so syntactically-valid YAML can't ship a workflow that GitHub Actions refuses to run. USE FOR: editing, adding, or reviewing any file under .github/workflows/, writing run-name/name/if/env/run values that contain ${{ }} expressions, diagnosing a run that fails with 'This run likely failed because of a workflow file issue' and no jobs starting, deciding when a workflow scalar must be quoted, validating workflows with actionlint. DO NOT USE FOR: authoring application YAML unrelated to GitHub Actions, Azure Pipelines, GitLab CI, or non-workflow YAML. SCOPE: this skill covers *syntactic/structural* correctness of workflow YAML (quoting, parsing, actionlint); for *semantic and functional* workflow design (what a workflow should do, agentic-workflow behavior), see .github/agents/agentic-workflows.agent.md — the two are complementary. INVOKES: actionlint (downloaded pinned binary) plus git/grep for inspection.
Creates VS Code custom agent files (.agent.md) for specialized AI personas with tools, instructions, and handoffs. Use when scaffolding new custom agents, configuring agent workflows, or setting up agent-to-agent handoffs.
Scaffolds eval.yaml evaluation specs for agent skills in the dotnet/skills repository. Use when creating skill tests, writing evaluation stimuli, defining graders and rubrics, sizing an eval for statistical power, or setting up test fixture files. Handles the Vally eval.yaml schema, fixture organization, and overfitting avoidance. Do not use for running or debugging existing evals (use improve-skill-quality) nor for skills authoring (use create-skill).
Scaffolds new agent skills for the dotnet/skills repository. Use when creating a new skill, generating SKILL.md files, writing a skill description that the runtime will actually route to, or setting up skill directory structures. Handles frontmatter generation, section templates, and validation guidance. Do not use for fixing a skill that already fails its evaluation (use improve-skill-quality) or for writing eval.yaml (use create-skill-test).
Diagnoses and fixes skills in the dotnet/skills repository that lose to their own baseline, fail to activate, time out, or return "no credible improvement". Use when an evaluation verdict is a regression or underpowered, when a skill regressed after a change, when /evaluate reports no results, or when deciding whether a weak skill should be strengthened or retired. Do not use for scaffolding a brand-new skill (use create-skill) or a brand-new eval (use create-skill-test).
Route gh-aw workflow design/create/debug/upgrade requests to the right prompts.
Run file-based C# apps with the .NET CLI when the user explicitly wants C#/.NET code without creating a project. Use for C# language/API experiments, one-file C# apps, small multi-file C# apps composed with `#:include`/`#:exclude`, or C# file-based apps linked with `#:ref`. Do not use for language-agnostic throwaway scripts, generic computations, Python/PowerShell-style automation, full projects, or existing app integration.
> Correctly call native (C/C++) libraries from .NET using P/Invoke and LibraryImport. Covers function signatures, string marshalling, memory lifetime, SafeHandle, and cross-platform patterns. existing native interop code, wrapping a C or C++ library for use in .NET, diagnosing crashes, memory leaks, or corruption at the managed/native boundary. no native dependencies.
> Set up NuGet trusted publishing (OIDC) on a GitHub Actions repo — replaces long-lived API keys migrate from NuGet API key, NuGet/login, secure NuGet publishing.
Guides technology selection and implementation of AI and ML features in .NET 8+ applications using ML.NET, Microsoft.Extensions.AI (MEAI), Microsoft Agent Framework (MAF), GitHub Copilot SDK, ONNX Runtime, and OllamaSharp. Covers the full spectrum from classic ML through modern LLM orchestration to local inference. Use when adding classification, regression, clustering, anomaly detection, recommendation, LLM integration (text generation, summarization, reasoning), RAG pipelines with vector search, agentic workflows with tool calling, Copilot extensions, or custom model inference via ONNX Runtime to a .NET project. DO NOT USE FOR projects targeting .NET Framework (requires .NET 8+), the task is pure data engineering or ETL with no ML/AI component, or the project needs a custom deep learning training loop (use Python with PyTorch/TensorFlow, then export to ONNX for .NET inference).
Configure OpenTelemetry distributed tracing, metrics, and logging in ASP.NET Core using the .NET OpenTelemetry SDK. Use when adding observability, setting up OTLP exporters, creating custom metrics/spans, or troubleshooting distributed trace correlation.
> Guides conversion of a pre-.NET 8 Blazor Server app into a .NET 8+ Blazor Web App. AddRazorComponents/MapRazorComponents model, converting _Host.cshtml to an App.razor root component, replacing blazor.server.js with blazor.web.js, migrating CascadingAuthenticationState to a service, adopting new Blazor Web App features like enhanced navigation and streaming rendering. and MapRazorComponents), Blazor WebAssembly or hosted Blazor WebAssembly apps (different migration path), apps that should stay on the Blazor Server hosting model without converting, or apps still targeting .NET Framework.
> Guides creation and modification of ASP.NET Core Web API endpoints with correct HTTP semantics, OpenAPI metadata, and error handling. OpenAPI/Swagger, creating .http test files, setting up global error handling middleware. optimization (use optimizing-ef-core-queries), frontend/Blazor work, gRPC services, or SignalR hubs.
File upload endpoints in ASP.NET minimal APIs (.NET 8+)
Claude Skills — questions
Answers built from the skills we actually parsed.