Use to choose or compare DSPy optimizers including LabeledFewShot, BootstrapFewShot, MIPROv2, SIMBA, GEPA, BootstrapFinetune, Ensemble, and BetterTogether.
npx skills add https://github.com/OmidZamani/dspy-skills --skill dspy-optimizer-selection
Choose the smallest DSPy optimizer that matches the data, budget, and artifact being tuned. Establish a baseline before compiling anything.
| Need | Start with | Notes |
|------|------------|-------|
| Include a few labeled examples | dspy.LabeledFewShot | Random labeled demos; useful as a baseline |
| About 10 examples | dspy.BootstrapFewShot | Teacher-generated demos with metric filtering |
| 50+ examples and stronger demo search | dspy.BootstrapFewShotWithRandomSearch | Searches multiple demo sets; alias: dspy.BootstrapRS |
| Per-input nearest demos | dspy.KNNFewShot | Retrieves nearby examples before bootstrapping |
| Instruction-only hill climbing | dspy.COPRO | Coordinate ascent over instructions |
| Instruction and demo search | dspy.MIPROv2 | Bayesian search; install dspy[optuna] |
| Mini-batch introspective rules or demos | dspy.SIMBA | Uses output variability and self-reflection |
| Rich textual feedback and trace reflection | dspy.GEPA | Metric must accept five arguments |
| Distill prompts into model weights | dspy.BootstrapFinetune | Requires a fine-tunable LM and set_lm() |
| Combine candidate programs | dspy.Ensemble | Trades inference cost for robustness |
| Sequence prompt and weight optimization | dspy.BetterTogether | Meta-optimizer for configurable optimizer chains |
Use dspy-bootstrap-fewshot for the first optimization pass. Move to BootstrapFewShotWithRandomSearch when enough examples are available to search multiple demo sets.
Use dspy-miprov2-optimizer for instruction and demonstration search. Install its optional dependency first:
pip install -U "dspy[optuna]>=3.2.1,<3.3"
Use dspy-gepa-reflective when failures can be described with actionable text. Use dspy-simba-optimizer for a smaller mini-batch introspective loop with numeric metrics.
Use dspy-better-together when a fine-tunable LM is available and prompt optimization alone has plateaued.
Integration with protocols.io API for managing scientific protocols. This skill should be used when working with protocols.io to search, create, update, or publish protocols; manage protocol steps and materials; handle discussions and comments; organize workspaces; upload and manage files; or integrate protocols.io functionality into workflows. Applicable for protocol discovery, collaborative protocol development, experiment tracking, lab protocol management, and scientific documentation.
Analyzes job descriptions and generates tailored resumes that highlight relevant experience, skills, and achievements to maximize interview chances
Generate Excalidraw diagrams from natural language descriptions. Use when asked to "create a diagram", "make a flowchart", "visualize a process", "draw a system architecture", "create a mind map", or "generate an Excalidraw file". Supports flowcharts, relationship diagrams, mind maps, and system architecture diagrams. Outputs .excalidraw JSON files that can be opened directly in Excalidraw.
Build and distribute Expo development clients locally or via TestFlight
Use when you have a written implementation plan to execute in a separate session with review checkpoints
Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.
Take omidzamani/dspy-optimizer-selection from the repository into ~/.claude/skills for personal
use, or into .claude/skills inside a project.
The agent identifies a skill by the name field in its header. Two skills with the
same name cannot sit side by side — one of them will be ignored.
The instructions reference pip.
Without those the skill loads but fails at the first command.