Database design principles and decision-making.
npx skills add https://github.com/Dokhacgiakhoa/Agent-Skills-4-Vibe-Coding-CLI --skill database-design
> Learn to THINK, not copy SQL patterns.
Read ONLY files relevant to the request! Check the content map, find what you need.
| File | Description | When to Read |
|------|-------------|--------------|
| database-selection.md | PostgreSQL vs Neon vs Turso vs SQLite | Choosing database |
| orm-selection.md | Drizzle vs Prisma vs Kysely | Choosing ORM |
| schema-design.md | Normalization, PKs, relationships | Designing schema |
| indexing.md | Index types, composite indexes | Performance tuning |
| optimization.md | N+1, EXPLAIN ANALYZE | Query optimization |
| migrations.md | Safe migrations, serverless DBs | Schema changes |
Before designing schema:
❌ Default to PostgreSQL for simple apps (SQLite may suffice)
❌ Skip indexing
❌ Use SELECT * in production
❌ Store JSON when structured data is better
❌ Ignore N+1 queries
Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.
Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.
Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.
Take dokhacgiakhoa/database-design from the repository into ~/.claude/skills for personal
use, or into .claude/skills inside a project.
The agent identifies a skill by the name field in its header. Two skills with the
same name cannot sit side by side — one of them will be ignored.