Geo Database Agent Skill

Geo Database

by christophacham

×4

Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.

Skill Optimizer

by rohitg00

SkillOpt-flavored offline training loop for any SKILL.md. Treats accumulated learn-rule corrections as training trajectories, proposes bounded patches via an optimizer LLM, gates each candidate against a held-out validation set built from the user's own past corrections, and ships only candidates that demonstrably improve the score. Inspired by Microsoft SkillOpt's ReflACT pipeline (rollout → reflect → aggregate → select → update → evaluate) adapted to pro-workflow's SQLite store. Use when a skill has accumulated 8+ learn-rule rows and the user wants the skill itself to get better, not just longer.

Bio Database Evidence

by foryourhealth111-pixel

Unified biological database evidence owner. Use for gene annotation, variant clinical significance, cancer mutation evidence, GWAS trait associations, pathway mapping, target-disease evidence, protein structures, protein interaction networks, reference single-cell census queries, and cross-database biological ID mapping. Do not use for full single-cell analysis, bulk RNA-seq differential expression, BAM/VCF processing, protein embedding models, metabolic flux modeling, genomic interval ML, or flow-cytometry file parsing.

Geo Database

by foryourhealth111-pixel

Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.

Ktx

by Kaelio

Installs and configures ktx, the open-source context layer for data agents — runs ktx setup non-interactively with hidden CLI flags, configures database connections and embeddings, installs agent integration, and verifies readiness. Use when the user asks an agent to add ktx to a project, connect data sources, install agent rules, ingest schema, or troubleshoot a local ktx install.

LLM Caching

by BagelHole

Implement multi-layer LLM caching with exact match, semantic similarity, and provider-side prompt caching. Reduce API costs by 30–70%, cut latency, and improve throughput using Redis, GPTCache, and provider caching APIs.

ReasoningBank with AgentDB

by spencermarx

Implement ReasoningBank adaptive learning with AgentDB's 150x faster vector database. Includes trajectory tracking, verdict judgment, memory distillation, and pattern recognition. Use when building self-learning agents, optimizing decision-making, or implementing experience replay systems.

Langchain4j Vector Stores Configuration

by giuseppe-trisciuoglio

Provides configuration patterns for LangChain4J vector stores in RAG applications. Use when building semantic search, integrating vector databases (PostgreSQL/pgvector, Pinecone, MongoDB, Milvus, Neo4j), implementing embedding storage/retrieval, setting up hybrid search, or optimizing vector database performance for production AI applications.