Machine Learning Skills

Use when the user is doing AI/ML work in a scientific domain such as biology, chemistry, physics, astronomy, climate, genomics, materials, medicine, ecology, energy, engineering, math, drug discovery, protein design, weather modeling, theorem proving, single-cell, or PDE solving. Hugging Science is a curated catalog of scientific datasets, models, blog posts, and interactive Spaces. This skill helps discover and use resources via `datasets`, `transformers`, the HF Inference API, `gradio_client`, and methodology citations.

Plans and audits use of ChicagoHAI HypoGeniC/HypoRefine for LLM-assisted hypothesis generation from labeled text datasets. Use for the `hypogenic` package, its task configs, hypothesis banks, or HypoBench datasets—not for manual hypothesis formulation or scientific validation.

Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.

Use when working with LaminDB, the open-source lineage-native lakehouse for biological datasets and models. Covers setup, artifact registration, query/search, lineage tracking, validation, ontology-backed annotation with Bionty, collections, branches, storage, and workflow integrations.

Modal is a serverless cloud platform for running Python on demand, including on-demand GPUs. Use when deploying or serving AI/ML models, running GPU-accelerated workloads (training, fine-tuning, inference), serving web endpoints, scheduling batch jobs, or scaling Python code to cloud containers with the Modal SDK.

> Query the 1000 Genomes Project dataset (3,202 whole-genome-sequenced individuals, GRCh38) at the level of individual participants. Use when a question is about individuals or variants in the 1000 Genomes in a gene or region, which individuals are homozygous-reference at a position, which variants exist in the dataset or carried by specified individuals in a gene or region, the relatedness between two specified individuals. Variants are returned with 1000 Genomes allele frequencies (AF), gnomAD v4.1 exome and genome AF, AlphaMissense score, and HGVSp annotations.

Hardware-agnostic quantum ML framework with automatic differentiation. Use when training quantum circuits via gradients, building hybrid quantum-classical models, or needing device portability across IBM/Google/Rigetti/IonQ. Best for variational algorithms (VQE, QAOA), quantum neural networks, and integration with PyTorch or JAX. For hardware-specific optimizations use qiskit (IBM) or cirq (Google); for open quantum systems use qutip.

Version-aware guidance for PufferLib reinforcement-learning environments, vectorization, policies, PuffeRL training, evaluation, and safe checkpoint review. Use when adapting Gymnasium/PettingZoo environments to published PufferLib 3.0.0 or working with the redesigned native 4.0 source line.

Use pydicom to read, inspect, write, transform, and safely preflight local DICOM datasets and pixel data. Applies to DICOM metadata, transfer syntaxes, compression plugins, frames, private elements, JSON, and bounded de-identification review.

Build clinical/healthcare deep-learning pipelines with PyHealth — loading EHR/signal/imaging datasets (MIMIC-III/IV, eICU, OMOP, SleepEDF, ChestXray14, EHRShot), defining tasks (mortality, readmission, length-of-stay, drug recommendation, sleep staging, ICD coding, EEG events), instantiating models (Transformer, RETAIN, GAMENet, SafeDrug, MICRON, StageNet, AdaCare, CNN/RNN/MLP), training with the PyHealth Trainer, computing clinical metrics, and using medical code utilities (ICD/ATC/NDC/RxNorm lookup and cross-mapping). Use this skill whenever the user mentions PyHealth, MIMIC, eICU, OMOP, EHR modeling, clinical prediction, drug recommendation, sleep staging, medical code mapping, ICD/ATC codes, or any healthcare ML pipeline that fits the dataset → task → model → trainer → metrics pattern, even if "PyHealth" isn't named explicitly.

Bayesian modeling with PyMC. Build hierarchical models, MCMC (NUTS), variational inference, LOO/WAIC comparison, posterior checks, for probabilistic programming and inference.

Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems.

Use Therapeutics Data Commons through the PyTDC Python package for registry discovery, approved dataset access, task-aware splits, evaluator metrics, benchmark groups, and bounded molecular-oracle workflows.

Deep learning framework (PyTorch Lightning / lightning package). Organize PyTorch code into LightningModules, configure Trainers for multi-GPU/TPU, implement data pipelines, callbacks, logging (W&B, TensorBoard, MLflow), distributed training (DDP, FSDP, DeepSpeed), for scalable neural network training.

Create publication-quality scientific diagrams using Nano Banana 2 AI with smart iterative refinement. Uses Gemini 3.6 Flash for quality review. Only regenerates if quality is below threshold for your document type. Specialized in neural network architectures, system diagrams, flowcharts, biological pathways, and complex scientific visualizations.

Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.

RNA velocity analysis with scVelo. Estimate cell state transitions from unspliced/spliced mRNA dynamics, infer trajectory directions, compute latent time, and identify driver genes in single-cell RNA-seq data. Complements Scanpy/scVI-tools for trajectory inference.

Production-ready reinforcement learning algorithms (PPO, SAC, DQN, TD3, DDPG, A2C) with scikit-learn-like API. Use for standard RL experiments, quick prototyping, and well-documented algorithm implementations. Best for single-agent RL with Gymnasium environments. For high-performance parallel training, multi-agent systems, or custom vectorized environments, use pufferlib instead.

Statistical models library for Python. Use when you need specific model classes (OLS, GLM, mixed models, ARIMA) with detailed diagnostics, residuals, and inference. Best for econometrics, time series, rigorous inference with coefficient tables. For guided statistical test selection with APA reporting use statistical-analysis.

Zero-shot time series forecasting with Google's TimesFM foundation model. Use for any univariate time series (sales, sensors, energy, vitals, weather) without training a custom model. Supports CSV/DataFrame/array inputs with point forecasts and prediction intervals. Includes a preflight system checker script to verify RAM/GPU before first use.

PyTorch Geometric (PyG) for graph neural networks — node/link/graph classification, message passing (GCN, GAT, GraphSAGE, GIN), heterogeneous graphs, neighbor sampling, and custom datasets. Use when working with torch_geometric, not for general NetworkX analytics or non-graph PyTorch models.

Build and troubleshoot TorchDrug 0.2.1 workflows for molecular graphs, property prediction, self-supervised pretraining, molecule generation, retrosynthesis, protein representation learning, and knowledge graph reasoning. Use when code imports torchdrug or needs its datasets, models, tasks, or Engine.

Use UMAP-learn for nonlinear dimensionality reduction, 2D/3D embeddings, clustering preprocessing, supervised or semi-supervised UMAP, DensMAP, AlignedUMAP, and Parametric UMAP workflows.

Add a persistent wiki knowledge base to a NanoClaw group. Based on Karpathy's LLM Wiki pattern. Triggers on "add wiki", "wiki", "knowledge base", "llm wiki", "karpathy wiki".

Answer questions about the AI SDK and help build AI-powered features. Use when developers: (1) Ask about AI SDK functions like generateText, streamText, ToolLoopAgent, embed, or tools, (2) Want to build AI agents, chatbots, RAG systems, or text generation features, (3) Have questions about AI providers (OpenAI, Anthropic, Google, etc.), streaming, tool calling, structured output, or embeddings, (4) Use React hooks like useChat or useCompletion. Triggers on: "AI SDK", "Vercel AI SDK", "generateText", "streamText", "add AI to my app", "build an agent", "tool calling", "structured output", "useChat".

Generate realistic dummy datasets for testing with customizable columns, constraints, and output formats (CSV, JSON, SQL, Python script). Use when creating test data, building mock datasets, or generating sample data for development and demos.

Profile and explore a dataset to understand its shape, quality, and patterns. Use when encountering a new table or file, checking null rates and column distributions, spotting data quality issues like duplicates or suspicious values, or deciding which dimensions and metrics to analyze.

Analyze compensation — benchmarking, band placement, and equity modeling. Trigger with "what should we pay a [role]", "is this offer competitive", "model this equity grant", or when uploading comp data to find outliers and retention risks.

> Analyzes unit economics by product or service using PayPal merchant insights and QuickBooks cost data, benchmarks against inflation and cost changes, and shows pricing-scenario data (e.g. "a 5% increase historically correlates with ~3% volume drop"). Surfaces analysis only — does not recommend a price. Use when the user asks about raising prices, pricing, margin analysis, what to charge, whether costs are eating into profit, or how a price change might affect their business. Trigger even if the user doesn't say "margin" explicitly — phrases like "am I making enough?", "should I charge more?", or "my costs are going up" all call for this skill.

> Claude as the trainer. Walks an SMB owner through connecting their first two tools, runs one recipe to prove immediate value, interviews them about their business (industry, size, top three headaches), stores that context persistently so every other skill benefits, and sets a weekly check-in "setup," "help me get set up," "get started," "help me get started," "get me started," "what can you do," "I'm new to this," or is in their first session.

Provide read-only NemoClaw maintainer policy. Use for questions about Issue Type, labels, Project fields, release labels, triage, duplicates, blocked items, and maintainer decisions. Trigger keywords - maintainer policy, workflow policy, project workflow, issue type, labels, label taxonomy, needs labels, project status, blocked issue, duplicate issue, daily release label, release train, triage policy.

Audit and fix out-of-range output writes in ONNX Runtime operator shape-inference functions. Use when reviewing or fixing a contrib (or standard) op TypeAndShapeInference where a getNumOutputs() guard precedes a write to a higher output index - optional trailing outputs make a smaller output count schema-valid, so getOutputType(index) can run one past the declared outputs at Graph::Resolve.

> Build, deploy, run, and benchmark Filament binaries on connected Android devices or emulators. Use this skill for compiling, pushing, and executing Android tests or benchmarks.

Train and fine-tune transformer language models using TRL (Transformers Reinforcement Learning). Supports SFT, DPO, GRPO, KTO, RLOO and Reward Model training via CLI commands.

查询 AI HOT 的中文 AI 资讯、精选、当前热点和日报。用户询问今天或最近的 AI 新闻、AI 圈动态、大模型或产品发布、OpenAI／Anthropic／Google 最新消息、AI 论文、AI 日报、AI HOT 精选、当前最热事件，或需要同步当前全部精选时使用。必须通过 aihot.virxact.com 的匿名只读 API 获取当前数据，不凭训练记忆回答新闻；不需要 API Key 或 MCP server。

Train or fine-tune sentence-transformers models across `SentenceTransformer` (bi-encoder; dense or static embedding model; for retrieval, similarity, clustering, classification, paraphrase mining, dedup, multimodal), `CrossEncoder` (reranker; pair scoring for two-stage retrieval / pair classification), and `SparseEncoder` (SPLADE, sparse embedding model; for learned-sparse retrieval). Covers loss selection, hard-negative mining, evaluators, distillation, LoRA, Matryoshka, and Hugging Face Hub publishing. Use for any sentence-transformers training task.

How to launch distributed Megatron-LM training jobs on a SLURM cluster. Covers a minimal sbatch skeleton, environment-variable setup for torch.distributed.run, CUDA_DEVICE_MAX_CONNECTIONS rules across hardware and parallelism modes, container conventions, monitoring, and per-rank failure diagnosis.

Migration guide for moving Megatron Core GPTModel checkpoints, model providers, training commands, and layer mappings to HybridModel.

KubeSphere Fluid management Skill. Use when user asks to install or enable Fluid, check Fluid status, view Fluid pods/logs/CRDs, create or update Dataset, AlluxioRuntime, JuiceFSRuntime, or ThinRuntime, perform DataLoad or cache warming, scale runtime, or troubleshoot Fluid issues in KubeSphere.

KubeSphere Volcano job management Skill. Use when user asks to create, list, update, delete Jobs (Volcano Jobs), manage Queues, create PyTorch/TensorFlow/MPI training jobs, or troubleshoot Volcano scheduling issues in KubeSphere. Includes built-in YAML templates, scheduling policy recommendations, and best practices for resource configuration. Handles both KubeSphere API and kubectl operations.

>- Measures and improves the quality of AI models and agents on Google Cloud using the Eval Quality Flywheel methodology. Use when evaluating an agent or model, building an eval dataset, picking or writing evaluation metrics, analyzing failures, comparing results before and after a fix, or when guidance is needed on Agent Platform eval methodology — including dataset schema, LLM-as-judge scoring, and common failure causes. For fine-tuning, use agent-platform-tuning. For general production deployment, use agent-platform-deploy.

>- Connects to and performs inference with Google Cloud Agent Platform GenAI models, including First-Party Gemini models and Third-Party OpenMaaS models (Llama, DeepSeek, Qwen, etc.). Use when you need to generate code for calling Gemini or OpenMaaS models, authenticate with GenAI SDK, OpenAI SDK, or legacy Agent Platform SDK, configure base URLs and global/regional endpoints, or troubleshoot 429 Resource Exhausted (DSQ), 400 User Validation, or 404 Not Found errors. Don't use for deploying models to endpoints or for running model evaluations.

>- Manage and query Agent Platform RAG Engine Corpora and retrieve grounded contexts using the Google GenAI SDK. Use when listing RAG corpora or files, inspecting a corpus, retrieving contexts, or generating content grounded in a RAG corpus. Do not use for standard database queries (use SQL/Spanner skills), Google Workspace RAG, or other RAG products like gRAG.

>- Manages GenAI tuning jobs in Agent Platform. Use this to list, get, or cancel ongoing model tuning jobs. Don't use for fine-tuning models (use `agent-platform-tuning`), deploying models to endpoints (use `agent-platform-deploy`), or managing serving endpoints (use `agent-platform-endpoint-management`).

>- Manages datasets, tables, and jobs in BigQuery. Use when you need to interact with BigQuery, run SQL queries, manage BigQuery resources (datasets, tables, views), or perform basic data ingestion and analysis.

>- Agent Platform Model Tuning. Use when you need to fine-tune open models or Gemini models using Agent Platform infrastructure. Don't use for model training outside Agent Platform, model deployment to endpoints (use `agent-platform-deploy`), or managing serving endpoints (use `agent-platform-endpoint-management`).

>- Diagnoses GKE JobSet interruptions, restarts, and preemptions for AI/ML training workloads autonomously. Use when troubleshooting JobSet restart loops, spot VM preemptions, node readiness failures, host VM issues, or coordinator worker crashes. Don't use for general GKE cluster creation, basic workload deployment, or non-JobSet application issues.

>- Plans and executes GKE cluster creation, provisioning, and production readiness audits using pre-defined templates (Autopilot, Standard Regional, GPU/AI Inference, AI Hypercompute). Use when creating GKE clusters, provisioning GKE environments, selecting cluster modes, or auditing GKE clusters. Don't use for application onboarding or deployment configuration (use gke-app-onboarding instead).