1 633 database skills from 232 authors. They work on schemas, queries and moving data between them. Half of them fit into 2 236 tokens or less — that is what one costs your context window when the agent loads it. 285 ship runnable scripts rather than instructions alone. 7 of them cannot work without an MCP server, most often rube. We also found 383 copies of these same skills sitting in other people's repositories — counted once here, not 383 times.
1 633 unique 232 authors 712 updated this month 156 from vendors
Query RCSB PDB (200K+ structures) via the public REST + GraphQL APIs with plain `requests` (no SDK). Search by text, attribute, sequence, or 3D structure similarity (Search API); retrieve metadata via GraphQL (Data API); download PDB/mmCIF from files.rcsb.org. For AlphaFold predictions use alphafold-database-access; for protein sequences only use uniprot-protein-database.
Search the PRIDE Archive v3 REST API for proteomics datasets: discover projects by keyword + faceted filters (organism, instrument, disease, software), fetch project metadata, list and download RAW/PEAK/RESULT/FASTA files (with FTP/Aspera URLs), look up which projects mention a UniProt accession, and find similar projects. PRIDE v3 no longer exposes peptide/PSM-level identification endpoints — for spectrum-level data download the project's RESULT files. Use uniprot-protein-database for protein sequences; interpro-database for domain architecture.
Query EBI QuickGO REST API for GO terms and protein annotations. Fetch term metadata by ID, search by keyword, walk ancestor/descendant hierarchies, download annotations filtered by taxon, evidence code, aspect. Use for GO resolution, ontology traversal, annotation retrieval before enrichment. Use gseapy-gene-enrichment for enrichment; uniprot-protein-database for proteins.
Query Reactome pathways via REST: pathway queries, entity lookup, keyword search, gene list enrichment, hierarchy, cross-refs. Content + Analysis services. Python wrapper: reactome2py. For KEGG use kegg-database; for PPIs use string-database-ppi.
Query RegulomeDB v2 GET REST API to score variants for regulatory function and retrieve overlapping evidence (TF binding, histone marks, DNase peaks, footprints, motifs, eQTLs, chromatin state). Scores range 1a (strongest) to 7 (none). Use for GWAS hit prioritization, regulatory variant annotation, cis-regulatory discovery. Use clinvar-database for pathogenicity; gwas-database for trait associations.
Query ReMap 2022 TF ChIP-seq peak database via REST API and BED downloads. Retrieve TF peaks overlapping a region (chr:start-end), peaks near a gene, TFs by species, peaks filtered by biotype (promoter, enhancer), and BED files for a TF-cell type pair. Use for TF co-occupancy, regulatory annotation, and TF binding atlases. Use jaspar-database for PWM motifs; encode-database for ENCODE tracks.
Query STRING REST API for PPIs (59M proteins, 20B interactions, 5000+ species). Retrieve networks, run GO/KEGG enrichment, find partners, test PPI significance, visualize networks, analyze homology. For chemical interactions use chembl-database-bioactivity; pathways use kegg-database.
Cross-reference compound IDs across 20+ databases (ChEMBL, DrugBank, PubChem, ChEBI, PDB, SureChEMBL, HMDB, DrugCentral, BindingDB) via UniChem REST API. Resolve InChIKeys to source IDs, translate between source-specific IDs, find structurally related compounds by connectivity. POST with a JSON body for all cross-reference queries; only /sources is GET. No auth required.
Access USPTO patent data via PatentsView REST API and Google Patents Public Data (BigQuery). Search by inventor, assignee, CPC, or keywords; download metadata and claims; analyze portfolios; track tech trends. For IP landscape analysis, competitor monitoring, prior art search, and tech forecasting in life sciences and biotech.
Query ZINC15/ZINC22 virtual compound libraries (1.4B compounds, 750M purchasable). Search lead/fragment/drug-like compounds by MW, logP, reactivity, or SMILES similarity; download 3D sets for docking. For bioactivity use chembl-database-bioactivity; for approved drugs use drugbank-database-access.
>- Provision instant temporary Postgres databases via Claimable Postgres by Neon (neon.new) with no login, signup, or credit card. Supports REST API, CLI, and SDK. Use when users ask for a quick Postgres environment, a throwaway DATABASE_URL for prototyping/tests, or "just give me a DB now". Triggers "no credit card database", "instant DATABASE_URL", "npx neon-new", "neon.new", "neon.new API", "claimable postgres API".
PostgreSQL-specific code review assistant focusing on PostgreSQL best practices, anti-patterns, and unique quality standards. Covers JSONB operations, array usage, custom types, schema design, function optimization, and PostgreSQL-exclusive security features like Row Level Security (RLS).
Work with MongoDB databases using best practices. Use when designing schemas, writing queries, building aggregation pipelines, or optimizing performance. Triggers on MongoDB, Mongoose, NoSQL, aggregation pipeline, document database, MongoDB Atlas.
Execute read-only SQL queries against multiple Microsoft SQL Server databases. Use when: (1) querying MSSQL/SQL Server databases, (2) exploring database schemas/tables, (3) running SELECT queries for data analysis, (4) checking database contents. Supports multiple database connections with descriptions for intelligent auto-selection. Blocks all write operations (INSERT, UPDATE, DELETE, DROP, etc.) for safety.
Execute read-only SQL queries against multiple MySQL databases. Use when: (1) querying MySQL databases, (2) exploring database schemas/tables, (3) running SELECT queries for data analysis, (4) checking database contents. Supports multiple database connections with descriptions for intelligent auto-selection. Blocks all write operations (INSERT, UPDATE, DELETE, DROP, etc.) for safety.
PostgreSQL-specific development assistant focusing on unique PostgreSQL features, advanced data types, and PostgreSQL-exclusive capabilities. Covers JSONB operations, array types, custom types, range/geometric types, full-text search, window functions, and PostgreSQL extensions ecosystem.
Design a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance patterns, and advanced features
Universal SQL performance optimization assistant for comprehensive query tuning, indexing strategies, and database performance analysis across all SQL databases (MySQL, PostgreSQL, SQL Server, Oracle). Provides execution plan analysis, pagination optimization, batch operations, and performance monitoring guidance.
Deploy applications on Railway platform. Use when deploying containerized apps, setting up databases, configuring private networking, or managing Railway projects. Triggers on Railway, railway.app, deploy container, Railway database.
SQLAlchemy and database patterns for Python. Triggers on: sqlalchemy, database, orm, migration, alembic, async database, connection pool, repository pattern, unit of work.
PostgreSQL database documentation - SQL queries, database design, administration, performance tuning, and advanced features. Use when working with PostgreSQL databases, writing SQL, or managing database systems.
TimescaleDB - PostgreSQL extension for high-performance time-series and event data analytics, hypertables, continuous aggregates, compression, and real-time analytics
PROACTIVELY query the code graph database to understand relationships and impact of changes. Use this skill WHEN READING any file to understand context, when searching for files, when exploring the codebase, or when you need to understand what depends on a component. This is your primary tool for understanding code structure and avoiding breaking changes.
Implement caching strategies using @delon/cache. Use this skill when adding memory cache, LocalStorage cache, SessionStorage cache, or cache interceptors for HTTP requests. Supports TTL-based expiration, cache invalidation, cache grouping, and persistent storage. Optimizes performance by reducing redundant API calls and database queries.
SQL query optimization and database performance specialist. Use when optimizing slow queries, fixing N+1 problems, designing indexes, implementing caching, or improving database performance. Works with PostgreSQL, MySQL, and other databases.
Comprehensive backend development skill for building scalable backend systems using NodeJS, Express, Go, Python, Postgres, GraphQL, REST APIs. Includes API scaffolding, database optimization, security implementation, and performance tuning. Use when designing APIs, optimizing database queries, implementing business logic, handling authentication/authorization, or reviewing backend code.
Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.
Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
Primary Python tool for 40+ bioinformatics services. Preferred for multi-database workflows: UniProt, KEGG, ChEMBL, PubChem, Reactome, QuickGO. Unified API for queries, ID mapping, pathway analysis. For direct REST control, use individual database skills (uniprot-database, kegg-database).
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.
Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.
Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.
Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.
Systematic database and table profiling for DBX Studio. Use when a user wants to understand their data, explore schema structure, or profile a dataset.
Systematic database and table profiling for DBX Studio. Use when a user wants to understand their data, explore schema structure, or profile a dataset.
Expert SQL query generation for DBX Studio. Use when writing, optimizing, or debugging SQL queries against user database connections.
Expert SQL query generation for DBX Studio. Use when writing, optimizing, or debugging SQL queries against user database connections.
Create reversible, focused database migrations with proper naming, version control practices, and zero-downtime deployment considerations. Use this skill when creating or editing migration files in database/migrations/, when writing schema changes (creating/modifying tables, columns, indexes, foreign keys), when implementing migration rollback methods, when managing database version control, when adding or modifying indexes on large tables, or when separating schema changes from data migrations for safer deployments.
Define and configure database models with proper naming, relationships, timestamps, data types, constraints, and validation. Use this skill when creating or editing model files in app/Models/, Eloquent model classes, model relationships (hasMany, belongsTo, etc.), database table structures, model attributes and casts, model factories, or seeders. Use when working on model validation logic, database constraints, foreign key relationships, indexes, scopes, accessors, mutators, or any ORM-related model configuration.
Write secure, performant, and optimized database queries using parameterized queries, eager loading, proper indexing, and transaction management. Use this skill when writing database queries in controllers, repositories, services, or model methods, when using query builders or ORM methods, when implementing filtering/sorting/pagination logic, when optimizing N+1 query problems with eager loading, when working with joins and complex queries, when implementing query caching, or when wrapping related operations in database transactions.
Expert guidance for Prisma ORM v7 (7.0+). Use when working with Prisma schema files, migrations, Prisma Client queries, database setup, or when the user mentions Prisma, schema.prisma, @prisma/client, database models, or ORM. Covers ESM modules, driver adapters, prisma.config.ts, Rust-free client, and migration from v6.
Master advanced AgentDB features including QUIC synchronization, multi-database management, custom distance metrics, and hybrid search for distributed AI systems.
Master advanced AgentDB features including QUIC synchronization, multi-database management, custom distance metrics, hybrid search, and distributed systems integration. Use when building distributed AI systems, multi-agent coordination, or advanced vector search applications.
Implement ReasoningBank adaptive learning with AgentDB's 150x faster vector database. Includes trajectory tracking, verdict judgment, memory distillation, and pattern recognition. Use when building self-learning agents, optimizing decision-making, or implementing experience replay systems.
Comprehensive backend development guide for Supabase Edge Functions + PostgreSQL. Use when working with Supabase (database, auth, storage, realtime), Edge Functions, PostgreSQL, Row-Level Security (RLS), Resend email, Stripe payments, or TypeScript backend patterns. Covers database design, auth flows, Edge Function patterns, RLS policies, email integration, payment processing, and deployment to Supabase.