Bio Causal Genomics Mendelian Randomization Agent Skill
Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.
Install
one command, takes just this skill from the repositorynpx skills add https://github.com/BioTender-max/awesome-bio-agent-skills --skill bio-causal-genomics-mendelian-randomizationOther skills for the same job
different authors, same section of the catalogue
Statistical visualization. Scatter, box, violin, heatmaps, pair plots, regression, correlation matrices, KDE, faceted plots, for exploratory analysis and publication figures.
Structured guide for setting up A/B tests with mandatory gates for hypothesis, metrics, and execution readiness.
Master dbt (data build tool) for analytics engineering with model organization, testing, documentation, and incremental strategies. Use when building data transformations, creating data models, or implementing analytics engineering best practices.
Master dbt (data build tool) for analytics engineering with model organization, testing, documentation, and incremental strategies. Use when building data transformations, creating data models, or implementing analytics engineering best practices.
Analyze ClickHouse Keeper stress-test results from play.clickhouse.com / keeper_stress_tests data warehouse. Use whenever the user asks about Keeper performance, validates Keeper PRs against stress dashboards, investigates regressions or improvements in Keeper nightlies, asks about specific date windows / SHAs / PR-sets in Keeper stress tests, wants per-PR or window-vs-window comparisons, asks "did this PR break Keeper", asks "what changed in Keeper between dates", or wants a summary report of Keeper stress runs. Triggers on terms like "keeper stress", "keeper PR", "keeper p99", "keeper memory", "keeper rps", "keeper nightly", "keeper-stress-tests", "keeper validation", "keeper regression", or any question referencing the keeper-stress Grafana dashboard. ALWAYS prefer this skill over re-deriving the workflow from scratch — it captures hard-learned lessons about cgroup-vs-Keeper memory, bench-harness confounds, noise floors, and per-PR attribution limits.
Master dbt (data build tool) for analytics engineering with model organization, testing, documentation, and incremental strategies. Use when building data transformations, creating data models, or implementing analytics engineering best practices.
Guide for writing tests for the Aspire Dashboard. Use this when asked to create, modify, or debug dashboard unit tests or Blazor component tests.
Render data visualizations with Canvas2D. Use when the visualization needs high mark counts, fast redraws, immediate-mode rendering, custom hit testing, or a hybrid Canvas plus SVG or HTML architecture.
How to use it
Take biotender-max/bio-causal-genomics-mendelian-randomization from the repository into ~/.claude/skills for personal
use, or into .claude/skills inside a project.
The agent identifies a skill by the name field in its header. Two skills with the
same name cannot sit side by side — one of them will be ignored.