UniProt MCP Server

by smaniches Your server? Claim it

local only

UniProt MCP runs on your own machine — the client starts it, so there is no endpoint to ping. 570 installs a week from pypi. Last commit 10 Sep 2026.

Verifiable, release-aware protein evidence workflows over UniProt and linked scientific sources.

Installs per day peak 256 · avg 56 · +75% w/w

a month agotoday

570

Installs / week

pypi · uniprot-mcp-server

Stars

0 open issues

10 Sep 2026

Last commit

0 releases in 90 days

Apache-2.0

License

Python

Nothing serious here today

Today is the operative word: we check UniProt MCP every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.

Connect this server

This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.

Claude Code Claude Desktop Codex Cursor VS Code

run in your terminal

claude mcp add uniprot-mcp -- uvx uniprot-mcp-server

~/Library/Application Support/Claude/claude_desktop_config.json

{
  "mcpServers": {
    "uniprot-mcp": {
      "args": [
        "uniprot-mcp-server"
      ],
      "command": "uvx"
    }
  }
}

~/.codex/config.toml

[mcp_servers.uniprot-mcp]
command = "uvx"
args = ["uniprot-mcp-server"]

.cursor/mcp.json

{
  "mcpServers": {
    "uniprot-mcp": {
      "args": [
        "uniprot-mcp-server"
      ],
      "command": "uvx"
    }
  }
}

.vscode/mcp.json

{
  "mcpServers": {
    "uniprot-mcp": {
      "args": [
        "uniprot-mcp-server"
      ],
      "command": "uvx"
    }
  }
}

Alternatives to UniProt MCP

same job, measured the same way

Openlane MCP Server

by gregdog

MCP server for Openlane GRC: controls, evidence, policies, risks, workflows, and approvals.

local only

minitok

by minitok

Verified coding workflows with planning, verification, bounded retries, evidence, and evolution.

837 installs/wk local only

Zevari

by zevari

Controlled LinkedIn and GTM MCP server with review-gated prospecting and outreach workflows.

answering

TMCP

by jakyeamos

Composable skill packets, harvests, workflow routing, and release/audit rubrics over MCP.

local only

FRAIM

by mathursrus

Accountable AI workforce workflows with jobs, skills, rules, evidence, and mentoring.

answering

Rancher MCP

by rex

Capability-aware MCP server for Rancher-managed Kubernetes: discovery, resources, workflows.

134 installs/wk local only

Hugging Bay

by barneywohl

Verified open AI artifact search, trust evidence, downloads, and agent workflows from Hugging Bay.

259 installs/wk 16 tools answering

Connext MCP

by rti

Integrate Connext AI into agentic workflows, enabling Connext product-aware assistance.

answering

UniProt MCP — questions

Answers built from our own checks of this server.

Why is there no uptime for UniProt MCP?

UniProt MCP runs on your own machine over stdio — there is no network address to reach, so uptime cannot be measured for it by anyone. What can be measured is adoption: the pypi package uniprot-mcp-server was installed 570 times last week.

How do I connect UniProt MCP?

Copy the ready config from this page — we generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each with the file path that client actually reads. It runs locally, so the command pulls uniprot-mcp-server straight from pypi; nothing to host, nothing to sign up for.

How many people use UniProt MCP?

The pypi package uniprot-mcp-server was installed 570 times in the last week. Week over week that is +75%. We show installs rather than GitHub stars on purpose: a star is a bookmark, an install is someone actually running it.

Is UniProt MCP open source?

Yes — it is published under the Apache-2.0 licence, written in Python and 3 stars on GitHub. The source link is on this page, so you can read exactly what it does with your data before you connect it.