UniProt MCP Server

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local only

UniProt MCP runs on your own machine — the client starts it, so there is no endpoint to ping. 1 172 installs a week from pypi. Last commit 2 Nov 2026.

Verifiable, release-aware protein evidence workflows over UniProt and linked scientific sources.

Installs per day peak 761 · avg 177 · -48% w/w

a month agotoday

1 172

Installs / week

pypi · uniprot-mcp-server

Stars

0 open issues

2 Nov 2026

Last commit

from GitHub

Apache-2.0

License

Python

Nothing serious here today

Today is the operative word: we check UniProt MCP every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.

Connect this server

This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.

Claude Code Claude Desktop Codex Cursor VS Code

run in your terminal

claude mcp add uniprot-mcp -- uvx uniprot-mcp-server

~/Library/Application Support/Claude/claude_desktop_config.json

{
  "mcpServers": {
    "uniprot-mcp": {
      "command": "uvx",
      "args": [
        "uniprot-mcp-server"
      ]
    }
  }
}

~/.codex/config.toml

[mcp_servers.uniprot-mcp]
command = "uvx"
args = ["uniprot-mcp-server"]

.cursor/mcp.json

{
  "mcpServers": {
    "uniprot-mcp": {
      "command": "uvx",
      "args": [
        "uniprot-mcp-server"
      ]
    }
  }
}

.vscode/mcp.json

{
  "servers": {
    "uniprot-mcp": {
      "type": "stdio",
      "command": "uvx",
      "args": [
        "uniprot-mcp-server"
      ]
    }
  }
}

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UniProt MCP — questions

Answers built from our own checks of this server.

Why is there no uptime for UniProt MCP?

UniProt MCP runs on your own machine over stdio — there is no network address to reach, so uptime cannot be measured for it by anyone. What can be measured is adoption: the pypi package uniprot-mcp-server was installed 1 172 times last week.

How do I connect UniProt MCP?

Copy the ready config from this page. We generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each in the form that client actually reads. It runs locally, so the command pulls uniprot-mcp-server straight from pypi; nothing to host, nothing to sign up for.

How many people use UniProt MCP?

The pypi package uniprot-mcp-server was installed 1 172 times in the last week. Week over week that is -48%. We show installs rather than GitHub stars on purpose: a star is a bookmark, an install is someone actually running it.

Is UniProt MCP open source?

Yes — it is published under the Apache-2.0 licence, written in Python and 3 stars on GitHub. The source link is on this page, so you can read exactly what it does with your data before you connect it.