BioCosm MCP Server

by nhoverte Your server? Claim it

answering

BioCosm is answering right now. Last checked 13 min ago. It exposes 13 tools.

Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.

Uptime history 91 days of history · worst day 42%

91 days agonow

100.0%

Uptime 24h

91 of 91 checks

Tools

read from the server

295 ms

Response time

average over 24h

open, no key

Access

streamable-http

Nothing serious here today

Today is the operative word: we check BioCosm every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.

Connect this server

Endpoint below is the one we actually reach during checks — not the one copied from a README. Last verified 13 min ago.

Claude Code Claude Desktop Codex Cursor VS Code

run in your terminal

claude mcp add biocosm --transport http https://biocosm-mcp.fly.dev/mcp

Settings → Connectors → Add custom connector, then paste this address

https://biocosm-mcp.fly.dev/mcp

~/.codex/config.toml

[mcp_servers.biocosm]
url = "https://biocosm-mcp.fly.dev/mcp"

.cursor/mcp.json

{
  "mcpServers": {
    "biocosm": {
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}

.vscode/mcp.json

{
  "servers": {
    "biocosm": {
      "type": "http",
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}

Available tools 13

Read directly from the server with tools/list, grouped by what they act on. If a tool disappears, we record the date.

node

get_node

Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when present), probability-of- success predictions for pipeline drugs (with confidence intervals and contributing factors), structured clinical trial outcomes, external cross-references, and writeup availability. Empty fields mean "not in BioCosm's coverage," NOT zero or absent in reality.

get_node_freshness

Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.

company

get_company_portfolio

Get a company's full drug/diagnostic portfolio from BioCosm.

coverage

get_coverage

Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.

nodes

search_nodes

Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form duplicates). Nodes matched only via description/company/area rank last. Each result includes a `name` field for disambiguation.

phase

find_by_phase

List drugs/diagnostics at a specific clinical phase.

pos

get_pos_score

Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).

find_related

Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node - "same_target_class": drugs with the same mechanism_class

staleness

get_staleness_report

Get writeup staleness report: overall stats, top stale nodes, data source freshness.

stats

get_stats

Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.

target

find_by_target

Find all drugs that target a specific gene/protein.

therapeutic

list_by_therapeutic_area

List all nodes in a given therapeutic area.

writeup

get_writeup

Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.

Endpoints

URL	Transport	State	Latency	Checked
https://biocosm-mcp.fly.dev/mcp	streamable-http	answering	347 ms	13 min ago

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BioCosm — questions

Answers built from our own checks of this server.

What can BioCosm do?

It exposes 13 tools, read directly from the server on our last check. Among them: find_by_phase, find_by_target, find_related, get_company_portfolio, get_coverage, get_node and 7 more. The full list with descriptions is on this page — we take it from the server itself via tools/list, not from a README. How MCP servers expose tools in the first place →

Is BioCosm working right now?

We send a real MCP handshake every 15 minutes. Over the last 24 hours 91 of 91 checks got a reply (100.0%), average response time 295 ms. The bar chart above shows every period we have measured.

How do I connect BioCosm?

Copy the ready config from this page. We generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each in the form that client actually reads. It is a remote server, so there is nothing to install — the client connects to the address.

Does BioCosm need an API key?

No. BioCosm completed a full MCP handshake with us as an anonymous client and listed its tools without asking for anything. All 13 of them are readable on this page. This is what we observed, not what the docs claim.

How fast is BioCosm?

It answers our handshake in 295 ms on average, which is faster than 47% of all working MCP servers we measure. The comparison comes from our own checks across the whole registry, every 15 minutes.