Reactome MCP runs on your own machine — the client starts it, so there is no endpoint to ping. Last commit 22 Sep 2026.
Keyless MCP server for Reactome: search biological pathways, get pathway details, species,...
Today is the operative word: we check Reactome MCP every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.
This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.
claude mcp add reactome-mcp -- npx -y reactome-mcp
{
"mcpServers": {
"reactome-mcp": {
"args": [
"-y",
"reactome-mcp"
],
"command": "npx"
}
}
}
[mcp_servers.reactome-mcp]
command = "npx"
args = ["-y", "reactome-mcp"]
{
"mcpServers": {
"reactome-mcp": {
"args": [
"-y",
"reactome-mcp"
],
"command": "npx"
}
}
}
{
"mcpServers": {
"reactome-mcp": {
"args": [
"-y",
"reactome-mcp"
],
"command": "npx"
}
}
}
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Answers built from our own checks of this server.