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UniProt MCP Server

local only

UniProt MCP runs on your own machine — the client starts it, so there is no endpoint to ping. 100 installs a week from pypi.

Read-only UniProtKB via MCP (entries, sequences, features, GO, taxonomy, ID mapping).

Installs per day peak 33 · avg 12 · +14% w/w
a month agotoday
100
Installs / week
pypi · uniprot-mcp
—
Stars
on GitHub
—
Last commit
from GitHub
—
License
language unknown

Nothing serious here today

Today is the operative word: we check UniProt MCP every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.

Three servers free · no card

Connect this server

This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.

run in your terminal
claude mcp add uniprot-mcp -- uvx uniprot-mcp
~/Library/Application Support/Claude/claude_desktop_config.json
{
  "mcpServers": {
    "uniprot-mcp": {
      "command": "uvx",
      "args": [
        "uniprot-mcp"
      ]
    }
  }
}
~/.codex/config.toml
[mcp_servers.uniprot-mcp]
command = "uvx"
args = ["uniprot-mcp"]
.cursor/mcp.json
{
  "mcpServers": {
    "uniprot-mcp": {
      "command": "uvx",
      "args": [
        "uniprot-mcp"
      ]
    }
  }
}
.vscode/mcp.json
{
  "servers": {
    "uniprot-mcp": {
      "type": "stdio",
      "command": "uvx",
      "args": [
        "uniprot-mcp"
      ]
    }
  }
}

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UniProt MCP — questions

Answers built from our own checks of this server.

Why is there no uptime for UniProt MCP?
UniProt MCP runs on your own machine over stdio — there is no network address to reach, so uptime cannot be measured for it by anyone. What can be measured is adoption: the pypi package uniprot-mcp was installed 100 times last week.
How do I connect UniProt MCP?
Copy the ready config from this page. We generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each in the form that client actually reads. It runs locally, so the command pulls uniprot-mcp straight from pypi; nothing to host, nothing to sign up for.
How many people use UniProt MCP?
The pypi package uniprot-mcp was installed 100 times in the last week. Week over week that is +14%. We show installs rather than GitHub stars on purpose: a star is a bookmark, an install is someone actually running it.