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DeepDNA local MCP Server

local only

DeepDNA local runs on your own machine — the client starts it, so there is no endpoint to ping. 234 installs a week from pypi. Last commit 25 Oct 2026.

Reads a raw DNA file on your computer and reports the variants DeepDNA curates, with sources.

Installs per day peak 272 · avg 16 · -14% w/w
a month agotoday
234
Installs / week
pypi · deepdna-mcp
0
Stars
1 open issue
25 Oct 2026
Last commit
from GitHub
MIT
License
Python

Nothing serious here today

Today is the operative word: we check DeepDNA local every 15 minutes and re-read its code on every release. Watch it and you find out the day that stops being true.

Three servers free · no card

Connect this server

This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.

run in your terminal
claude mcp add local -- uvx deepdna-mcp
~/Library/Application Support/Claude/claude_desktop_config.json
{
  "mcpServers": {
    "local": {
      "command": "uvx",
      "args": [
        "deepdna-mcp"
      ]
    }
  }
}
~/.codex/config.toml
[mcp_servers.local]
command = "uvx"
args = ["deepdna-mcp"]
.cursor/mcp.json
{
  "mcpServers": {
    "local": {
      "command": "uvx",
      "args": [
        "deepdna-mcp"
      ]
    }
  }
}
.vscode/mcp.json
{
  "servers": {
    "local": {
      "type": "stdio",
      "command": "uvx",
      "args": [
        "deepdna-mcp"
      ]
    }
  }
}

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DeepDNA local — questions

Answers built from our own checks of this server.

Why is there no uptime for DeepDNA local?
DeepDNA local runs on your own machine over stdio — there is no network address to reach, so uptime cannot be measured for it by anyone. What can be measured is adoption: the pypi package deepdna-mcp was installed 234 times last week.
How do I connect DeepDNA local?
Copy the ready config from this page. We generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each in the form that client actually reads. It runs locally, so the command pulls deepdna-mcp straight from pypi; nothing to host, nothing to sign up for.
How many people use DeepDNA local?
The pypi package deepdna-mcp was installed 234 times in the last week. Week over week that is -14%. We show installs rather than GitHub stars on purpose: a star is a bookmark, an install is someone actually running it.
Is DeepDNA local open source?
Yes — it is published under the MIT licence, written in Python, 0 stars on GitHub and 1 open issue. The source link is on this page, so you can read exactly what it does with your data before you connect it.