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Rosetta MCP Server

local only

Rosetta MCP Server runs on your own machine — the client starts it, so there is no endpoint to ping. 89 installs a week from npm. Last commit 5 Apr 2026.

Rosetta/PyRosetta protein modeling and Biotite translation for computational biology

Installs per day peak 40 · avg 12 · -36% w/w
a month agotoday
89
Installs / week
npm · rosetta-mcp-server
19
Stars
1 open issue
5 Apr 2026
Last commit
no releases in 90 days
MIT
License
JavaScript

What the code does

We read the source, 4 d ago · rules 995398eba69f

A tool parameter reaches a dangerous call

A value the model can set ends up inside a file or shell call. That is not a flaw by itself — for a terminal server it is the job — but it is where things go wrong when it is not.

A tool parameter reaches a dangerous call search_rosetta_web_docs.max_results → rosetta_mcp_wrapper.js:1232, translate_rosetta_script_to_biotite.max_results → rosetta_mcp_wrapper.js:1232
            const proc = spawn(py, ['-c', script], {
Capabilities

What this server is able to do. For an MCP server this is often the job itself — a terminal server runs commands because that is what it is for. Listed so you know what you are plugging in, not as an accusation.

            const proc = spawn(py, ['-c', script]);
                    if (match) return path.join(p, match);
Long encoded blob in source rosetta_mcp_http.js:261
        const iconB64 = 'iVBORw0KGgoAAAANSUhEUgAAAgAAAAIACAYAAAD0eNT6AAAJcUlEQVR4nO3YsW3jWhRFUfqDVQiMVYg6UBkMVIIil8BAZbgDFuJ4MLkTB078u5gb7LUaeAeUDWzct5/vr98FAEj5b3oAAPDvCQAACBIAABAkAAAgSAAAQJAAAIAgAQAAQQIAAIIEAAAECQAACBIAABAkAAAgSAAAQJAAAIAgAQAAQQIAAIIEAAAECQAACBIAABAkAAAgSAAAQJA…

Is this your server and something here is wrong? Tell us — corrections are free and do not require a plan.

A tool parameter here reaches a dangerous call

That is not a flaw by itself — but it is where things go wrong when it is not the job. We re-read this code on every release. Watch it and you hear from us the day another one appears.

Three servers free · no card

Connect this server

This server runs on your own machine — install it with the package manager and the client starts it for you. Package name taken from the official registry entry.

run in your terminal
claude mcp add rosetta-mcp-server -- npx -y rosetta-mcp-server
~/Library/Application Support/Claude/claude_desktop_config.json
{
  "mcpServers": {
    "rosetta-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "rosetta-mcp-server"
      ]
    }
  }
}
~/.codex/config.toml
[mcp_servers.rosetta-mcp-server]
command = "npx"
args = ["-y", "rosetta-mcp-server"]
.cursor/mcp.json
{
  "mcpServers": {
    "rosetta-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "rosetta-mcp-server"
      ]
    }
  }
}
.vscode/mcp.json
{
  "servers": {
    "rosetta-mcp-server": {
      "type": "stdio",
      "command": "npx",
      "args": [
        "-y",
        "rosetta-mcp-server"
      ]
    }
  }
}

Optional settings from the registry entry, left out of the block above: ROSETTA_BIN (Path to rosetta_scripts binary or its directory), PYTHON_BIN (Python interpreter with PyRosetta/Biotite installed), MCP_DEBUG (Set to 1 for debug logging).

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Rosetta MCP Server — questions

Answers built from our own checks of this server.

Why is there no uptime for Rosetta MCP Server?
Rosetta MCP Server runs on your own machine over stdio — there is no network address to reach, so uptime cannot be measured for it by anyone. What can be measured is adoption: the npm package rosetta-mcp-server was installed 89 times last week.
How do I connect Rosetta MCP Server?
Copy the ready config from this page. We generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each in the form that client actually reads. It runs locally, so the command pulls rosetta-mcp-server straight from npm; nothing to host, nothing to sign up for.
How many people use Rosetta MCP Server?
The npm package rosetta-mcp-server was installed 89 times in the last week. Week over week that is -36%. We show installs rather than GitHub stars on purpose: a star is a bookmark, an install is someone actually running it.
Is Rosetta MCP Server open source?
Yes — it is published under the MIT licence, written in JavaScript, 19 stars on GitHub and 1 open issue. The source link is on this page, so you can read exactly what it does with your data before you connect it.