Machine Learning Claude Skills
1 780 machine learning skills from 282 authors. They train and fine-tune models, build embeddings, run RAG and measure quality. Half of them fit into 2 252 tokens or less — that is what one costs your context window when the agent loads it. 424 ship runnable scripts rather than instructions alone. 10 of them cannot work without an MCP server, most often rube. We also found 397 copies of these same skills sitting in other people's repositories — counted once here, not 397 times.
1 780 unique 282 authors 5 updated this month 189 from vendors
| Process split datasets into training, validation, and testing sets for ML model development. Use when requesting "split dataset", "train-test split", or "data partitioning". Trigger with relevant phrases based on skill purpose.
| Streaming Inference Setup - Auto-activating skill for ML Deployment. Part of the ML Deployment skill category.
| Tensorboard Visualizer - Auto-activating skill for ML Training. Part of the ML Training skill category.
| Tensorflow Model Trainer - Auto-activating skill for ML Training. Part of the ML Training skill category.
| Train Test Splitter - Auto-activating skill for ML Training. Part of the ML Training skill category.
| Build train machine learning models with automated workflows. Analyzes datasets, selects model types (classification, regression), configures parameters, trains with cross-validation, and saves model artifacts. Use when asked to "train model" or "evalua... Trigger with relevant phrases based on skill purpose.
| This skill automates the adaptation of pre-trained machine learning models using transfer learning techniques. It is triggered when the user requests assistance with fine-tuning a model, adapting a pre-trained model to a new dataset, or performing transfer learning. It analyzes the user's requirements, generates code for adapting the model, includes data validation and error handling, provides performance metrics, and saves artifacts with documentation. Use this skill when you need to leverage existing models for new tasks or datasets, optimizing for performance and efficiency.
| Triton Inference Config - Auto-activating skill for ML Deployment. Part of the ML Deployment skill category.
| Validate AI/ML models and datasets for bias, fairness, and ethical concerns. Use when auditing AI systems for ethical compliance, fairness assessment, or bias detection. Trigger with phrases like "evaluate model fairness", "check for bias", or "validate AI ethics".
Build and deploy production-ready generative AI agents using Vertex AI, Gemini models, and Google Cloud infrastructure with RAG, function calling, and multi-modal capabilities
| Wandb Experiment Logger - Auto-activating skill for ML Training. Part of the ML Training skill category.
Cloudflare Vectorize vector database for semantic search and RAG. Use for vector indexes, embeddings, similarity search, or encountering dimension mismatches, filter errors. nearest neighbor, knn search, ann search, RAG, retrieval augmented generation, chat with data, document search, semantic Q&A, context retrieval, bge-base, @cf/baai/bge-base-en-v1.5, text-embedding-3-small, text-embedding-3-large, Workers AI embeddings, openai embeddings, insert vectors, upsert vectors, query vectors, delete vectors, metadata filtering, namespace filtering, topK search, cosine similarity, euclidean distance, dot product, wrangler vectorize, metadata index, create vectorize index, vectorize dimensions, vectorize metric, vectorize binding
Cloudflare Workers AI for serverless GPU inference. Use for LLMs, text/image generation, embeddings, or encountering AI_ERROR, rate limits, token exceeded errors. ai inference, cloudflare llm, ai streaming, text generation ai, ai embeddings, image generation ai, workers ai rag, ai gateway, llama workers, flux image generation, stable diffusion workers, vision models ai, ai chat completion, AI_ERROR, rate limit ai, model not found, token limit exceeded, neurons exceeded, ai quota exceeded, streaming failed, model unavailable, workers ai hono, ai gateway workers, vercel ai sdk workers, openai compatible workers, workers ai vectorize
ElevenLabs Agents Platform for AI voice agents (React/JS/Native/Swift). Use for voice AI, RAG, tools, or encountering package deprecation, audio cutoff, CSP violations, webhook auth failures.
Google Gemini embeddings API (gemini-embedding-001) for RAG and semantic search. Use for vector search, Vectorize integration, or encountering dimension mismatches, rate limits, text truncation.
Google Gemini File Search for managed RAG with 100+ file formats. Use for document Q&A, knowledge bases, or encountering immutability errors, quota issues, polling failures. Supports Gemini 3 Pro/Flash (Gemini 2.5 legacy).
Type-safe Hono APIs with routing, middleware, RPC. Use for request validation, Zod/Valibot validators, or encountering middleware type inference, validation hook, RPC errors.
| Rates any SKILL.md on a 0-100 scale across 10 dimensions with a SHIP / REWORK / SCRAP verdict. Evaluates trigger precision, instruction clarity, output predictability, edge case coverage, anti-hallucination guardrails, developer experience, composability, open-source readiness, wow factor, and real-world utility. No flattery — calibrated against Anthropic's own skill-creator rubric. Use this skill whenever someone says "score this skill", "rate my skill", "is this skill good", "skill review", "skill audit", "roast my SKILL.md", "grade this", "will this skill work", "evaluate my skill", "how good is this", or pastes a SKILL.md and asks for feedback. Also trigger when comparing two skills, benchmarking a skill collection, or asking "what's wrong with this skill" — even without the word "score".
Analyze Apple Health export ZIP. Run local prepare to generate structured insights, then produce complementary health and training reports with long-term context.
为城市旅行明信片、城市拼贴海报生成可直接用于图像模型的完整提示词。用户提到城市明信片、旅行拼贴、城市视觉海报、生图提示词，或在视觉创作上下文中输入城市、城市+国家、节日、季节、活动时，应使用本 skill；即使用户只给出城市名，也要在上下文明确为视觉创作时使用。不用于旅游攻略、行程规划或普通城市事实问答。
Creates new skills, modifies and improves existing skills, and measures skill performance. Use when users want to create a skill from scratch, update or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or optimize a skill's description for better triggering accuracy.
Investigate AI observability clusters — understand usage patterns in AI/LLM traffic, compare cluster behavior, compute cost/latency metrics, and drill into individual traces within clusters.
> Investigate AI observability evaluations of both types — `hog` (deterministic code-based) and `llm_judge` (LLM-prompt-based). Find existing evaluations, inspect their configuration, run them against specific generations, query individual pass/fail results, and generate AI-powered summaries of patterns across many runs. Use when the user asks to debug why an evaluation is failing, surface common failure modes, compare results across filters, dry-run a Hog evaluator, prototype a new LLM-judge prompt, or manage the evaluation lifecycle (create, update, enable/disable, delete).
>- Add PostHog LLM analytics to trace AI model usage. Use after implementing LLM features or reviewing PRs to ensure all generations are captured with token counts, latency, and costs. Also handles initial PostHog SDK setup if not yet installed.
PostHog LLM analytics for all supported providers
>- Add PostHog LLM analytics to trace AI model usage. Use after implementing LLM features or reviewing PRs to ensure all generations are captured with token counts, latency, and costs. Also handles initial PostHog SDK setup if not yet installed.
Predict protein 3D structures with AlphaFold2 via ColabFold — MMseqs2-accelerated MSAs, monomer and AlphaFold2-Multimer complex folding, and confidence-based validation (pLDDT, pTM/ipTM, PAE). Use when folding a protein sequence or complex from FASTA, generating a predicted structure with confidence metrics, ranking models, or checking self-consistency of a design. For co-folding a protein WITH a small-molecule ligand or predicting binding affinity prefer alterlab-boltz; for antibody–antigen or one-FASTA multi-entity complexes prefer alterlab-chai; to LOOK UP an already-computed structure prefer alterlab-alphafold-db; for ESM embeddings or inverse folding prefer alterlab-esm. Part of the AlterLab Academic Skills suite.
Infer gene regulatory networks (GRNs) from expression matrices using arboreto's scalable GRNBoost2 and GENIE3 tree-ensemble algorithms with Dask-distributed computation. Use when analyzing bulk or single-cell RNA-seq transcriptomics to map transcription-factor-to-target-gene regulatory interactions, build adjacency networks, or run the GRN-inference step of a SCENIC pipeline on large datasets. Part of the AlterLab Academic Skills suite.
Query the CZ CELLxGENE Census (61M+ cells) programmatically via cellxgene-census and TileDB-SOMA, slicing expression by tissue, disease, or cell type and returning AnnData. Use when pulling reference single-cell RNA-seq data from the largest curated public atlas, running population-scale queries, or benchmarking your data against a reference — for analyzing your own dataset use scanpy or scvi-tools. Part of the AlterLab Academic Skills suite.
Run ESM protein language models — ESM3 for generative multimodal protein design across sequence, structure, and function, and ESM C for efficient embeddings and representations — locally or via the cloud Forge API. Use when working with protein sequences, structures, or function prediction, designing novel proteins, generating protein embeddings, performing inverse folding, or doing protein-engineering tasks. Part of the AlterLab Academic Skills suite.
Manage, annotate, and trace biological data with LaminDB, an open-source FAIR data framework that makes datasets queryable, versioned, and reproducible. Use when registering or querying biological datasets (scRNA-seq, spatial, flow cytometry), validating and curating data against ontologies (genes, cell types, diseases, tissues), tracking data lineage and computational workflows, building data lakehouses, or wiring integrations with Nextflow, Snakemake, W&B, or MLflow. Part of the AlterLab Academic Skills suite.
Extract and preprocess tiles from whole-slide images (WSI) with histolab — OpenSlide-backed slide loading, tissue detection and masks, Random/Grid/Score tile extraction, and image/morphological filters for H&E preprocessing. Use when the user needs lightweight WSI slide preprocessing — building tile datasets for ML training, tissue segmentation, or quick tile-based inspection of histopathology slides. For end-to-end computational-pathology, deep-learning model training, nucleus segmentation, or multiplexed/spatial-proteomics (CODEX, Vectra) pipelines prefer alterlab-pathml instead. Part of the AlterLab Academic Skills suite.
Run full computational-pathology workflows with PathML — whole-slide-image (WSI) analysis across 160+ slide formats, multiplexed immunofluorescence (CODEX, Vectra, MERFISH), nucleus segmentation/classification (HoVer-Net, HACTNet), tissue- and cell-graph construction, HDF5 dataset management, and deep-learning model training on pathology data. Use when the user builds end-to-end deep-learning pathology pipelines, analyzes multiplexed or spatial-proteomics slides, or segments nuclei. For lightweight H&E slide preprocessing, tissue masking, or plain Random/Grid/Score tile extraction prefer alterlab-histolab instead. Part of the AlterLab Academic Skills suite.
Analyze Neuropixels 1.0/2.0 extracellular electrophysiology with SpikeInterface — load SpikeGLX/Open Ephys recordings, preprocess and motion-correct, run Kilosort4 spike sorting, compute quality metrics, apply Allen/IBL curation, and do AI-assisted visual inspection. Use when working with neural recordings, spike sorting, or extracellular electrophysiology, or when the user mentions Neuropixels, SpikeGLX, Open Ephys, Kilosort, quality metrics, or unit curation. Part of the AlterLab Academic Skills suite.
Build phylogenetic trees end-to-end from raw sequences — MAFFT multiple sequence alignment, optional TrimAl trimming, IQ-TREE 2 maximum-likelihood inference with model selection and bootstraps, FastTree for large datasets, then visualize with ETE3 or FigTree. Use when reconstructing trees from sequences (FASTA) for evolutionary analysis, microbial genomics, viral phylodynamics, protein-family studies, or molecular-clock dating. For manipulating/comparing an EXISTING Newick tree (prune, root, Robinson-Foulds, duplication/speciation events) use alterlab-etetoolkit; for plain sequence parsing/translation use alterlab-biopython. Part of the AlterLab Academic Skills suite.
Apply the scGPT single-cell foundation model (Cui 2024) to annotate and embed cells — zero-shot and fine-tuned cell-type annotation, gene/cell embeddings, batch integration, and gene-regulatory / perturbation inference from AnnData. Use when annotating cell types with a pretrained foundation model, generating scGPT embeddings, integrating batches with a transformer, or running zero-shot single-cell inference on an h5ad. For probabilistic latent models (scVI/scANVI) prefer alterlab-scvi-tools; for the standard QC→cluster→UMAP→DE pipeline prefer alterlab-scanpy; for the AnnData data structure itself prefer alterlab-anndata; for protein language models prefer alterlab-esm. Part of the AlterLab Academic Skills suite.
Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome). Use when correcting batch effects, integrating multimodal data, or doing advanced probabilistic single-cell modeling — for standard analysis pipelines use scanpy. Part of the AlterLab Academic Skills suite.
Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for flat VCF, building joint variant stores, or querying thousands of samples by region. Part of the AlterLab Academic Skills suite.
Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end molecular ML experiments that need MoleculeNet benchmarks, scaffold splitting, or ready-made models with minimal setup; for building custom PyTorch graph architectures prefer alterlab-torchdrug, and for standalone molecule-to-feature-vector generation prefer alterlab-molfeat. Part of the AlterLab Academic Skills suite.
Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark dataset, applying scaffold or cold-split evaluation, or sourcing labeled molecules for ADMET, toxicity, or DTI modeling. Sources data, splits, and oracles only — defer molecular featurization (ECFP/fingerprints), model training, and transformers to a molecular-ML skill (e.g. deepchem). Part of the AlterLab Academic Skills suite.
Featurizes molecules for machine learning with molfeat (100+ featurizers) — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, GIN) exposed as scikit-learn transformers that convert SMILES into feature vectors. Use when turning molecules into ML-ready feature matrices for QSAR/QSPR or virtual screening, or benchmarking fingerprint against descriptor and embedding representations; for training models and MoleculeNet benchmarks on those features prefer alterlab-deepchem, and for low-level fingerprint or descriptor primitives prefer alterlab-rdkit. Part of the AlterLab Academic Skills suite.
Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), with cloud compute and no local setup. Use when running DFT or semiempirical methods, neural network potentials (AIMNet2), molecular property or protein-ligand binding predictions, or automated computational chemistry pipelines. Part of the AlterLab Academic Skills suite.
Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when developing custom graph model layers, predicting protein properties from sequence or structure, or building retrosynthesis and drug-repurposing pipelines; for ready-made featurizers, MoleculeNet benchmarks, and pre-trained models with less code prefer alterlab-deepchem. Part of the AlterLab Academic Skills suite.