mcpbeat

BioCosm MCP Server

io.github.nhoverte/biocosm
answering

BioCosm is answering right now. Last checked 15 min ago. It exposes 13 tools.

Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.

Uptime history 44 hours of history
44 hours agonow
100.0%
Uptime 24h
91 of 91 checks
13
Tools
read from the server
314 ms
Response time
average over 24h
open, no key
Access
streamable-http

Connect this server

Endpoint below is the one we actually reach during checks — not the one copied from a README. Last verified 15 min ago.

run in your terminal
claude mcp add biocosm --transport http https://biocosm-mcp.fly.dev/mcp
~/Library/Application Support/Claude/claude_desktop_config.json
{
  "mcpServers": {
    "biocosm": {
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}
~/.codex/config.toml
[mcp_servers.biocosm]
url = "https://biocosm-mcp.fly.dev/mcp"
.cursor/mcp.json
{
  "mcpServers": {
    "biocosm": {
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}
.vscode/mcp.json
{
  "mcpServers": {
    "biocosm": {
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}

Available tools 13

Read directly from the server with tools/list, grouped by what they act on. If a tool disappears, we record the date.

node
get_node
Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when present), probability-of- success predictions for pipeline drugs (with confidence intervals and contributing factors), structured clinical trial outcomes, external cross-references, and writeup availability. Empty fields mean "not in BioCosm's coverage," NOT zero or absent in reality.
get_node_freshness
Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.
company
get_company_portfolio
Get a company's full drug/diagnostic portfolio from BioCosm.
coverage
get_coverage
Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.
nodes
search_nodes
Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form duplicates). Nodes matched only via description/company/area rank last. Each result includes a `name` field for disambiguation.
phase
find_by_phase
List drugs/diagnostics at a specific clinical phase.
pos
get_pos_score
Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).
related
find_related
Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node - "same_target_class": drugs with the same mechanism_class
staleness
get_staleness_report
Get writeup staleness report: overall stats, top stale nodes, data source freshness.
stats
get_stats
Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.
target
find_by_target
Find all drugs that target a specific gene/protein.
therapeutic
list_by_therapeutic_area
List all nodes in a given therapeutic area.
writeup
get_writeup
Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.

Endpoints

URLTransportStateLatencyChecked
https://biocosm-mcp.fly.dev/mcp streamable-http answering 344 ms 15 min ago

BioCosm — questions

Answers built from our own checks of this server.

What can BioCosm do?
It exposes 13 tools, read directly from the server on our last check. Among them: find_by_phase, find_by_target, find_related, get_company_portfolio, get_coverage, get_node and 7 more. The full list with descriptions is on this page — we take it from the server itself via tools/list, not from a README. How MCP servers expose tools in the first place →
Is BioCosm working right now?
We send a real MCP handshake every 15 minutes. Over the last 24 hours 91 of 91 checks got a reply (100.0%), average response time 314 ms. The bar chart above shows every period we have measured.
How do I connect BioCosm?
Copy the ready config from this page — we generate it for Claude Code, Claude Desktop, Codex, Cursor and VS Code, each with the file path that client actually reads. It is a remote server, so there is nothing to install — the client connects to the address.
Does BioCosm need an API key?
No. BioCosm completed a full MCP handshake with us as an anonymous client and listed its tools without asking for anything. All 13 of them are readable on this page. This is what we observed, not what the docs claim.
How fast is BioCosm?
It answers our handshake in 314 ms on average, which is faster than 45% of all working MCP servers we measure. The comparison comes from our own checks across the whole registry, every 15 minutes.